Retinal pathologies, like ARMD or glaucoma, need to be early detected, requiring imaging instruments with resolution at
a cellular scale. However, in vivo retinal cells studies and early diagnoses are severely limited by the lack of resolution
on eye-fundus images from classical ophthalmologic instruments. We built a 2D retina imager using Adaptive Optics to
improve lateral resolution. This imager is currently used in clinical environment. We are currently developing a time
domain full-field optical coherence tomograph. The first step was to conceive the images reconstruction algorithms and
validation was realized on non-biological samples. Ex vivo retina are currently being imaged. The final step will consist
in coupling both setups to acquire high resolution retina cross-sections.
We describe here two parts of our future 3D fundus camera coupling Adaptive Optics and full-field Optical Coherence Tomography. The first part is an Adaptive Optics flood imager installed at the Quinze-Vingts Hospital, regularly used on healthy and pathological eyes. A posteriori image reconstruction is performed, increasing the final image quality and field of view. The instrument lateral resolution is better than 2 microns. The second part is a full-field Optical Coherence Tomograph, which has demonstrated capability of performing a simple kind of "4 phases" image reconstruction of non biological samples and ex situ retinas. Final aim is to couple both parts in order to achieve 3D high resolution mapping of in vivo retinas.
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