Few-cycle intense THz pulses and the process of the second harmonic generation are appealing techniques for excitation and investigation of ultrafast dynamic response of magnetically ordered systems, ferroelectrics and multiferroics at the picosecond timescale. In this study, we report on experimental findings on the optical second harmonic generation in the centrosymmetric antiferromagnetic NiO induced by intense THz pulses with electric fields up to 20 MV/cm.
We report on the investigation of the biological effects of high-power pulsed broadband terahertz (THz) radiation on human skin fibroblasts. Cells were exposed to THz pulses with peak intensity ~30 GW/cm2 and electrical field strength ~3.5 MV/cm for 1.5 hours. Phosphorylation of H2AX (γH2AX foci) can be caused by different reasons including DNA double stand breaks, heat induction and can be related to chromosomes stability. However, the γH2AX foci seem to be a proper marker for detection of the effect of intense terahertz pulses on cells. The kinetics of phosphorylated histone H2AX foci post terahertz radiation exposure is analyzed. We found that the number of phosphorylated H2AX foci in human skin fibroblasts remained almost unchanged within 24 hours following terahertz exposure.
We present experimental results on measurement of free-carrier dynamics in p-type silicon crystal in high electric fields of THz pulses in the MV/cm range. Carrier recombination dynamics in p-type silicon is analyzed through time-resolved pump-probe experiments in which THz pulse is used as a pump, and a femtosecond optical pulse is used as a probe.
Near-infrared femtosecond laser pulses were applied to initiate reversible permeabilization of cell membrane and inject extrinsic substances into the target cells. Successful laser-based injection of a membrane impermeable dye, as well as plasmid DNA was demonstrated.
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