Mr. Pieter S. Verduijn Profile

Pieter S. Verduijn

at Leiden University Medical Center

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 7 March 2019 Presentation + Paper

Perfusion assessment of DIEP flaps based on near-infrared fluorescence imaging: current literature and pilot study

P. Verduijn, M. Michi, A. Vahrmeijer, B. Sibinga Mulder

Proceedings Volume 10862, 1086213 (2019) https://doi.org/10.1117/12.2522281

KEYWORDS: Surgery, Breast, Luminescence, Tissues, Indocyanine green, Arteries, Ischemia, Angiography, Imaging systems, Capillaries

Read Abstract +

The most common complication of autologous breast reconstructions using a deep inferior epigastric artery (DIEP) flap after mastectomy is fat necrosis due to ischemia. DIEP flap perfusion assessment can be optimized by using nearinfrared fluorescence (NIRF) imaging with indocyanine green (ICG). Several studies demonstrated diminished incidence of fat necrosis, partial flap loss and other complications. Studies with large patient numbers and standardized outcomes are lacking. To determine the correlation of incidence of fat necrosis and NIRF imaging with ICG we performed: 1) a review to evaluate relevant literature, and 2) a pilot study of NIRF imaging. With the aim to decide whether a randomized controlled trial (RCT) should be started. Seven studies were included in the review, showing NIRF imaging was feasible and incidence of fat necrosis was diminished. However, most studies were retrospective and with small patient numbers. In the pilot study, 18 flaps, assessed with NIRF imaging were prospectively included and compared to 18 retrospectively included flaps solely assessed based on clinical findings. There were no significant differences in patient and surgery characteristics. Incidence of complications and fat necrosis decreased from 30% to 6% (p-value: 0.07) in the NIRF imaging group. No strong conclusions can be drawn from the pilot study given the low patient number, neither from the reviewed studies. But based on the results a multicenter RCT would be recommended to determine the actual value of NIRF imaging for perfusion assessment of DIEP flaps. An RCT could also aid in wider implementation of this accessible technique in a standardized matter.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years