Mr. Robert Lathrop Profile

Robert Lathrop

at Smith & Nephew Inc

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Proceedings Article | 22 February 2017 Paper

Histological evaluation and optimization of surgical vessel sealing systems

Robert Lathrop, Thomas Ryan, Jonathan Gaspredes, Jean Woloszko, James Coad

Proceedings Volume 10066, 100660T (2017) https://doi.org/10.1117/12.2255912

KEYWORDS: Tissues, Surgery, Laparoscopy, Thermal effects, Blood vessels, Medical device development, Arteries, Homogenization, Collagen, Proteins

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Surgical vessel sealing systems are widely used to achieve hemostasis and dissection in open surgery and minimally invasive, laparoscopic surgery. This enabling technology was developed about 17 years ago and continues to evolve with new devices and systems achieving improved outcomes. Histopathological assessment of thermally sealed tissues is a valuable tool for refining and comparing performance among surgical vessel sealing systems. Early work in this field typically assessed seal time, burst rate, and failure rate (in-situ). Later work compared histological staining methods with birefringence to assess the extent of thermal damage to tissues adjacent to the device. Understanding the microscopic architecture of a sealed vessel is crucial to optimizing the performance of power delivery algorithms and device design parameters. Manufacturers rely on these techniques to develop new products. A system for histopathological evaluation of vessels and sealing performance was established, to enable the direct assessment of a treatment’s tissue effects. The parameters included the commonly used seal time, pressure burst rate and failure rate, as well as extensions of the assessment to include its likelihood to form steam vacuoles, adjacent thermal effect near the device, and extent of thermally affected tissue extruded back into the vessel lumen. This comprehensive assessment method provides an improved means of assessing the quality of a sealed vessel and understanding the exact mechanisms which create an optimally sealed vessel.

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