Dr. Timothy M. Baran Profile

Dr. Timothy M. Baran

Assistant Professor at University of Rochester

SPIE Involvement:

Conference Program Committee | Author

Area of Expertise:

Tissue optics , Photodynamic Therapy

Publications (18)

SPIE Journal Paper | 28 February 2024 Open Access

Application of transfer learning for rapid calibration of spatially resolved diffuse reflectance probes for extraction of tissue optical properties

Md Nafiz Hannan, Timothy Baran

JBO, Vol. 29, Issue 02, 027004, (February 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.2.027004

KEYWORDS: Artificial neural networks, Optical properties, Education and training, Scattering, Machine learning, Calibration, Sensors, Absorption, Data modeling, Biomedical applications

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SPIE Journal Paper | 27 February 2024 Open Access

First in human measurements of abscess cavity optical properties and methylene blue uptake prior to photodynamic therapy by in vivo diffuse reflectance spectroscopy

Md Nafiz Hannan, Ashwani K. Sharma, Timothy Baran

JBO, Vol. 29, Issue 02, 027002, (February 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.2.027002

KEYWORDS: Optical properties, Photodynamic therapy, Diffuse reflectance spectroscopy, Absorption, Sensors, Optical testing, Optical spectroscopy, Spectroscopy, Scattering, Oxygen

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Proceedings Article | 17 March 2023 Poster

Localization of a molecularly targeted probe for imaging and photodynamic therapy of breast cancer in a murine model

Zihao Li, Joseph Majeski, Regine Choe, Hans Schmitthenner, Timothy Baran

Proceedings Volume PC12359, PC123590D (2023) https://doi.org/10.1117/12.2648451

KEYWORDS: Photodynamic therapy, Breast cancer, Tumor growth modeling, Tumors, Surgery, Luminescence, In vivo imaging, Near infrared, Microscopy, Cancer

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Proceedings Article | 14 March 2023 Poster + Paper

Preliminary measurements of optical properties in human abscess cavities prior to methylene blue photodynamic therapy

Md. Nafiz Hannan, Ashwani Sharma, Timothy Baran

Proceedings Volume 12359, 123590A (2023) https://doi.org/10.1117/12.2648453

KEYWORDS: Optical properties, Photodynamic therapy, Diffuse reflectance spectroscopy, Tissues, Scattering, Clinical trials, Absorption, Oxygen, Monte Carlo methods, Fiber optics

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Proceedings Article | 14 March 2023 Presentation + Paper

Methylene blue photodynamic therapy of bacterial species found in human abscesses: planktonic, biofilm, and 3D silicone models

Helen Chan, Martin Pavelka, Timothy Baran

Proceedings Volume 12358, 1235805 (2023) https://doi.org/10.1117/12.2648350

KEYWORDS: 3D modeling, Biofilms, Photodynamic therapy, Bacteria, Computed tomography, 3D image processing

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Proceedings Article | 7 March 2022 Presentation

Recovery of optical properties for antimicrobial photodynamic therapy treatment planning using a compact optical probe

Karina Bridger, Jacob Roccabruna, Timothy Baran

Proceedings Volume PC11940, (2022) https://doi.org/10.1117/12.2608900

KEYWORDS: Optical properties, Photodynamic therapy, Scattering, Safety, Monte Carlo methods, Clinical trials, Absorption, Tissues, Spectroscopy, Sensors

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Proceedings Article | 7 March 2022 Poster

Patient-specific treatment planning improves eligibility for photodynamic therapy of deep tissue abscess cavities: retrospective simulation study

Zihao Li, Lam Nguyen, David Bass, Timothy Baran

Proceedings Volume PC11939, PC1193909 (2022) https://doi.org/10.1117/12.2608898

KEYWORDS: Monte Carlo methods, Photodynamic therapy, Absorption, Tissue optics, Tissues, Optical properties, Computed tomography, Scattering

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SPIE Journal Paper | 11 February 2022 Open Access

Effects of patient-specific treatment planning on eligibility for photodynamic therapy of deep tissue abscess cavities: retrospective Monte Carlo simulation study

Zihao Li, Lam Nguyen, David Bass, Timothy Baran

JBO, Vol. 27, Issue 08, 083007, (February 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.8.083007

KEYWORDS: Absorption, Photodynamic therapy, Optical properties, Scattering, Monte Carlo methods, Tissue optics, Tissues, Image segmentation, Bladder, Computed tomography

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Proceedings Article | 5 March 2021 Presentation

Methylene blue photodynamic therapy to sterilize deep tissue abscess cavities: a phase 1 trial in progress and simulation study

Timothy Baran, Lam Nguyen, Thomas Foster, Ashwani Sharma

Proceedings Volume 11626, 116260N (2021) https://doi.org/10.1117/12.2575949

KEYWORDS: Monte Carlo methods, Photodynamic therapy, Tissue optics, Optical properties, Tissues, Safety, Resistance, Optical spectroscopy, In vivo imaging, Device simulation

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Proceedings Article | 4 March 2019 Presentation

Methylene blue photodynamic therapy for treatment of deep tissue abscess cavities (Conference Presentation)

Timothy Baran, Mattison Flakus, Hyun Choi

Proceedings Volume 10860, 108600J (2019) https://doi.org/10.1117/12.2506177

KEYWORDS: Photodynamic therapy, Tissue optics, Image segmentation, Monte Carlo methods, Tissues, Resistance, Clinical trials, Safety, Computed tomography

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SPIE Journal Paper | 22 July 2016 Open Access

Recovery of optical properties using interstitial cylindrical diffusers as source and detector fibers

Timothy Baran

JBO, Vol. 21, Issue 07, 077001, (July 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.7.077001

KEYWORDS: Diffusers, Optical fibers, Sensors, Optical properties, Signal detection, Absorption, Scattering, Tumors, Spectroscopy, Tissue optics

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Proceedings Article | 1 March 2016 Paper

Intratumor photosensitizer injection for photodynamic therapy: Pre-clinical experience with methylene blue, Pc 4, and Photofrin

Timothy Baran, Thomas Foster

Proceedings Volume 9694, 969418 (2016) https://doi.org/10.1117/12.2229544

KEYWORDS: Photodynamic therapy, Tissue optics, Animal model studies, Tumors, Information technology, Skin, Eye, Biopsy

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SPIE Journal Paper | 3 April 2015 Open Access

Cylindrical diffuser axial detection profile is dependent on fiber design

Timothy Baran

JBO, Vol. 20, Issue 04, 040502, (April 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.4.040502

KEYWORDS: Diffusers, Monte Carlo methods, Photons, Scattering, Reflectors, Sensors, Dielectrics, Photodynamic therapy, Tissue optics, Solids

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Proceedings Article | 2 March 2015 Paper

Use of cylindrical diffusing fibers as detectors for interstitial tissue spectroscopy

Timothy Baran, Thomas Foster

Proceedings Volume 9308, 93080J (2015) https://doi.org/10.1117/12.2085543

KEYWORDS: Diffusers, Optical fibers, Sensors, Scattering, Optical properties, Tissue optics, Spectroscopy, Monte Carlo methods, Reflectors, Photodynamic therapy

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Proceedings Article | 14 April 2014 Paper

Recovery of optical properties from interstitial spectroscopy for photodynamic therapy treatment planning

Timothy Baran, Michael Fenn, Thomas Foster

Proceedings Volume 8931, 89310K (2014) https://doi.org/10.1117/12.2037808

KEYWORDS: Optical fibers, Spectroscopy, Optical properties, Photodynamic therapy, Sensors, Scattering, Monte Carlo methods, Absorption, Photodetectors, Solids

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SPIE Journal Paper | 22 October 2013 Open Access

Determination of optical properties by interstitial white light spectroscopy using a custom fiber optic probe

Timothy Baran, Michael Fenn, Thomas Foster

JBO, Vol. 18, Issue 10, 107007, (October 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.10.107007

KEYWORDS: Optical properties, Spectroscopy, Scattering, Absorption, Sensors, Tissue optics, Solids, Oxygen, Signal detection, Monte Carlo methods

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SPIE Journal Paper | 17 September 2012 Open Access

Optical property measurements establish the feasibility of photodynamic therapy as a minimally invasive intervention for tumors of the kidney

Timothy Baran, Jeremy Wilson, Soumya Mitra, Jorge Yao, Edward Messing, David Waldman, Thomas Foster

JBO, Vol. 17, Issue 9, 098002, (September 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.9.098002

KEYWORDS: Tumors, Kidney, Optical properties, Optical fibers, Photodynamic therapy, Diffuse reflectance spectroscopy, Optical testing, Tissue optics, Absorption, Diffusers

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SPIE Journal Paper | 1 August 2011 Open Access

New Monte Carlo model of cylindrical diffusing fibers illustrates axially heterogeneous fluorescence detection: simulation and experimental validation

Timothy Baran, Thomas Foster

JBO, Vol. 16, Issue 08, 085003, (August 2011) https://doi.org/10.1117/12.10.1117/1.3613920

KEYWORDS: Diffusers, Luminescence, Optical fibers, Monte Carlo methods, Fluorescence spectroscopy, Photons, Scattering, Absorption, Tissue optics, Optical properties

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Showing 5 of 18 publications

Conference Committee Involvement (4)

Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2025

27 January 2025 | San Francisco, California, United States

Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2024

29 January 2024 | San Francisco, California, United States

Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2023

28 January 2023 | San Francisco, California, United States

Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2022

21 February 2022 | San Francisco, California, United States

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