Optical coherence tomography has been employed to expose and map micron-level cardiac tissue structures. Previous studies have characterized structural substrates like collagen fibers, adipose tissue, scar tissue, and the pulmonary vein region. Cardiac fiber orientation plays a critical role in the electromechanics of the human atria but it has yet to be quantitatively evaluated. Therefore, personalized fiber orientation atlases produced by algorithmic mapping of atrial fiber geometry can serve as models for studying the mechanisms behind AF and cardiac arrhythmias overall. Integration of this algorithm may eventually provide important insights for the guidance of RFA procedures as well.
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