KEYWORDS: Brain, Neuroimaging, Hemodynamics, Acquisition tracking and pointing, Photoacoustic tomography, Photoacoustic spectroscopy, In vivo imaging, Brain mapping, Visualization, Imaging systems
While medical imaging is playing an increasingly important role in understanding and clarifying acupuncture theory in general, it is still challenging to systematically understand the operational mechanisms of acupuncture on the central and peripheral nerve systems using the existing acupuncture imaging tools. Here, we report an application of photoacoustic tomography (PAT) to mapping cerebral hemodynamics response to acupuncture in mice. Huantiao acupoint (GB 30) is selected as the stimulating points in this study. In vivo photoacoustic images of cerebral hemodynamics response to acupuncture are obtained in ten functional regions of a mouse brain. Real-time photoacoustic signal changes in brain cortex and dynamic changes in total hemoglobin (HbT) concentration are tracked at 532 nm. Our results suggest that PAT provides imaging basis on cerebral hemodynamic response to acupuncture, and may have great potential for understanding the operational mechanisms of acupuncture on the central nerve systems.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.