Living cell culture provides convenient and standard biotechnology chosen option in the laboratory. However, current imaging methods could not present real 3D models. Therefore, we have developed a compact, high-speed spectral-domain optical coherence microscopy (SD-OCM) system to observe the interaction of the tumor cell spheroid with gold nanoparticles. Volumetric OCM images of the cell spheroid were acquired using an in-house C++ interface and used a low-cost microcontroller for triggering to synchronize the galvanometer mirror to the detector array. We designed a hermetic chamber on the microscope stage to control temperature, humidity, CO2 concentration in the experiment.
The inner ear is a small and sophisticated organ, mainly comprising of the vestibular system and cochlea, responsible for hearing function and plays a crucial role in the life wellness.There have been several studies of investigating the cochlear structures with OCT, and most of these studies used OCT systems with a central wavelength of 1.3 µm. However, the utility of 1 µm OCT system for cochlear imaging application has yet been explored albeit the capability of providing OCT images with a higher axial resolution. Therefore, in this study, we have developed a 1.3 µm and a 1 µm OCT system allowing quantitative and spectroscopic comparison of the cochlear microstructures.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.