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METAFIP is an image analysis system designed to find cells in metaphase state on a microscope slide for subsequent recall, and eventually to rank them in accordance with some quality criteria. It is based on the Fast Interval Processor (FIP), a high speed image analyser, which scans the image using a linear charge coupled diode array. Slide scan rates of tsq mm./sec. have been achieved without saturating the computer. An 8MHz stream of pixel density values is reduced to a data rate which can be digested in a fast minicomputer using interval coding. The paper describes how the interval parameters (or features) extracted by the hard-wired preprocesser are used by the metaphase finding algorithms. Results are given showing encouraging discrimination between metaphase and nonmetaphase cells on a variety of materials.
Geoffrey Shippey,Royston Bayley, andErik Granum
"Metaphase Finding Using A Fast Interval Processer, Metafip", Proc. SPIE 0375, Medical Imaging and Image Interpretation, (1 November 1982); https://doi.org/10.1117/12.934664
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Geoffrey Shippey, Royston Bayley, Erik Granum, "Metaphase Finding Using A Fast Interval Processer, Metafip," Proc. SPIE 0375, Medical Imaging and Image Interpretation, (1 November 1982); https://doi.org/10.1117/12.934664