Indium Labeled Platelet Deposition Following CO2 Laser Or Surgical Endarterectomy

John H. McVicker; Arthur L. Day; James M. Seeger

doi:10.1117/12.952038

11 September 1989 Indium Labeled Platelet Deposition Following CO₂ Laser Or Surgical Endarterectomy

John H. McVicker, Arthur L. Day, James M. Seeger

Proceedings Volume 1066, Laser Surgery: Advanced Characterization, Therapeutics, and Systems; (1989) https://doi.org/10.1117/12.952038
Event: OE/LASE '89, 1989, Los Angeles, CA, United States

Abstract

Endovascular damage from CO₂, Nd:YAG, or argon laser can be considerable, causing reduced vascular biosynthesis of prostacyclin and precipitating platelet aggregation. However, the degree of platelet thrombus formation has not been directly quantified. Using Indium labeled platelets, platelet accumulation after low radiant energy CO₂ laser endarterectomy was compared to accumulation after standard microsurgical endarterectomy in normal canine carotid arteries. Undisturbed adjacent segments from the same arteries served as controls. Platelet deposition (Indium activity per minute per milligram arterial tissue) was significantly greater on laser treated segments than on surgical (p=0.002) or control (p=0.002) segments. This confirms prior histologic evidence of increased acute platelet deposition after CO₂ laser endarterectomy and suggests the need for further investigation of the thrombogenicity of laser angioplasty.

Citation Download Citation

John H. McVicker, Arthur L. Day, and James M. Seeger "Indium Labeled Platelet Deposition Following CO₂ Laser Or Surgical Endarterectomy", Proc. SPIE 1066, Laser Surgery: Advanced Characterization, Therapeutics, and Systems, (11 September 1989); https://doi.org/10.1117/12.952038

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KEYWORDS

Arteries

Control systems

Laser therapeutics

Carbon dioxide lasers

Argon ion lasers

Laser vision correction

Laser energy

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