Refractive index detection of nanolitre samples in a microfluidic chip with a Michelson interferometer

Yangcheng Luo; Huiqing Chen; Kun Liu; Changyong Zhu; Junshan Liu

doi:10.1117/12.2503854

12 December 2018 Refractive index detection of nanolitre samples in a microfluidic chip with a Michelson interferometer

Yangcheng Luo, Huiqing Chen, Kun Liu, Changyong Zhu, Junshan Liu

Proceedings Volume 10848, Micro-Optics and MOEMS; 1084804 (2018) https://doi.org/10.1117/12.2503854
Event: International Symposium on Optoelectronic Technology and Application 2018, 2018, Beijing, China

Abstract

A Michelson interferometer is designed for the refractive index detection of nanolitre samples in a microfluidic chip. A He-Ne laser beam (power of 0.5mW) is divided into a detection beam and a reference beam by a beam splitter. Equal inclination interference patterns (circular fringes) formed by the reference beam and the detection beam passing through the chip channel (width of 65μm and depth of 50μm) are observed clearly. The intensity of the central part of the interference pattern changes while rotating the chip. Signals of the light intensity versus the rotation angle are collected by a detector (consisted of a fiber and a photomultiplier) and recorded by a computer. By rotating the chip from 0° to +17°, signals are measured when the chip channel is filled with air, water and sodium hydroxide solution NaOH (with a refractive index of 1.3450). Fitting the signal curves with Origin program in a theoretical equation, the refractive indices of air, water and NaOH solution in the chip channel are derived. The results coincided basically with those measured by an Abbe refractometer.

Citation Download Citation

Yangcheng Luo, Huiqing Chen, Kun Liu, Changyong Zhu, and Junshan Liu " Refractive index detection of nanolitre samples in a microfluidic chip with a Michelson interferometer", Proc. SPIE 10848, Micro-Optics and MOEMS, 1084804 (12 December 2018); https://doi.org/10.1117/12.2503854

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KEYWORDS

Water

Sensors

Microfluidics

Michelson interferometers

Refractive index

Beam splitters

Neodymium

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