Local and global transformations to improve learning of medical images applied to chest radiographs

Vidya M. S.; Manikanda Krishnan V.; Anirudh G.; Srinivasa Rao Kundeti; Vijayananda J.

doi:10.1117/12.2512717

15 March 2019 Local and global transformations to improve learning of medical images applied to chest radiographs

Vidya M. S., Manikanda Krishnan V., Anirudh G., Srinivasa Rao Kundeti, Vijayananda J.

Proceedings Volume 10949, Medical Imaging 2019: Image Processing; 1094936 (2019) https://doi.org/10.1117/12.2512717
Event: SPIE Medical Imaging, 2019, San Diego, California, United States

Abstract

A potential drawback of computer-aided diagnosis (CAD) systems is that they tend to capture the noise characteristics along with signal variations due to a limited number of sources used in training. This leads to a decrease in performance on data from different sources. The variations in scanner settings, device manufacturers and sites pose a significant challenge to the learning capabilities of the CAD systems like chest radiographs, also called Chest X-rays (CXR). In the proposed work, we investigate if preprocessing transformations like global normalization along with local enhancements are good to tackle the variability of data from multiple sources on a supervised CXR classification system. We also propose a detail enhancement filter to enhance both finer structures and opacities in CXRs. With the proposed preprocessing improvement, experiments were performed on 13,000 images across 3 public and one private data source using Dense Convolutional Network (DenseNet). The sensitivity at equal error rate (mean ± sd) improved from 0.888 ± 0.043 to 0.931 ± 0.030 by applying a combination of global histogram equalization with the proposed detail enhancement filter when compared to the raw images. We conclude that the proposed transformations are effective in improving the learning of CXRs from different data sources.

Citation Download Citation

Vidya M. S., Manikanda Krishnan V., Anirudh G., Srinivasa Rao Kundeti, and Vijayananda J. "Local and global transformations to improve learning of medical images applied to chest radiographs ", Proc. SPIE 10949, Medical Imaging 2019: Image Processing, 1094936 (15 March 2019); https://doi.org/10.1117/12.2512717

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