CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11079 > Article
Paper
22 July 2019 Laser irradiation induces mitochondrial dysfunction in hepatic cells
Anna Lynnyk, Barbora Smolková, Mariia Uzhytchak, Daria Egorova, Andrei Kulikov, Mariia Lunova, Šárka Kubinová, Alexandr Dejneka, Oleg Lunov
Author Affiliations +
Proceedings Volume 11079, Medical Laser Applications and Laser-Tissue Interactions IX; 1107911 (2019) https://doi.org/10.1117/12.2527110
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany
Abstract
Laser irradiation has been recognized as a promising tool across a number of biomedical applications. However, understanding the molecular mechanisms and cellular responses remains incomplete. Here, we investigated the mechanism involved in the apoptotic process in human hepatic cells under laser irradiation. Our data show that the laser-mediated alternation of mitochondrial membrane potential leads apoptosis in Huh7 and Alexander cells. Contrary, HepG2 cells are resistant to laser induced cell death. The observed link between mitochondrial membrane potential and cytotoxicity could be a fundamental phenomenon in laser-induced cell apoptosis.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Anna Lynnyk, Barbora Smolková, Mariia Uzhytchak, Daria Egorova, Andrei Kulikov, Mariia Lunova, Šárka Kubinová, Alexandr Dejneka, and Oleg Lunov "Laser irradiation induces mitochondrial dysfunction in hepatic cells", Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 1107911 (22 July 2019); https://doi.org/10.1117/12.2527110
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 4 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Luminescence
Bioalcohols
Medical research
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top