Wavelength dependence of ultrahigh resolution optical coherence tomography using supercontinuum for deep imaging

Norihiko Nishizawa; Masahito Yamanaka

doi:10.1117/12.2573216

15 June 2020 Wavelength dependence of ultrahigh resolution optical coherence tomography using supercontinuum for deep imaging

Norihiko Nishizawa, Masahito Yamanaka

Author Affiliations +

Proceedings Volume 11521, Biomedical Imaging and Sensing Conference 2020; 1152107 (2020) https://doi.org/10.1117/12.2573216
Event: SPIE Technologies and Applications of Structured Light, 2020, Yokohama, Japan

Abstract

Optical coherence tomography (OCT) is a non-invasive cross-sectional imaging technique with micrometer resolution. We have been investigating ultrahigh-resolution (UHR)-OCT using supercontinuum. The characteristics of OCT imaging depend on the optical wavelength used. In order to investigate the wavelength dependence of UHR-OCT, the wideband, high-power, low-noise supercontinua were generated at wavelengths of 0.8, 1.1, 1.3, and 1.7 um based on ultrashort pulses and nonlinear fibers. The wavelength dependence of OCT imaging was examined quantitatively using biological phantoms and rat lung tissue. Then we developed UHR-spectral domain-OCT and optical coherence microscopy (OCM) at 1.7 um. The high-resolution and high-penetration imaging of mouse brain was demonstrated.

Citation Download Citation

Norihiko Nishizawa and Masahito Yamanaka "Wavelength dependence of ultrahigh resolution optical coherence tomography using supercontinuum for deep imaging", Proc. SPIE 11521, Biomedical Imaging and Sensing Conference 2020, 1152107 (15 June 2020); https://doi.org/10.1117/12.2573216

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