CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11647 > Article
Presentation
5 March 2021 Bioprinting 3D angiogenesis models with Laser Induced Side Transfer
Sayadeh Sara Hosseini Kolkooh, Hamid Ebrahimi Orimi, Erika Hooker, Sivakumar Narayanswamy, Bruno Larrivee, Christos Boutopoulos
Author Affiliations +
Proceedings Volume 11647, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX; 116471D (2021) https://doi.org/10.1117/12.2584573
Event: SPIE BiOS, 2021, Online Only
Abstract
The ability to generate 3D angiogenesis models is central for tissue engineering and drug screening applications. However, existing bio-fabrication technologies have yet to attain precise guidance of capillary networks in 3D. Here, we present our latest results in fabricating capillary networks using a novel laser-assisted bioprinting technique named Laser Induced Side Transfer (LIST). We found that LIST-printed human umbilical vein endothelial cells (HUVECs) present negligible loss of viability and maintain their abilities to migrate, proliferate and form intercellular junctions. Furthermore, we showed that LIST enabled the formation of capillary-like networks in 3D with high spatial precision (50 μm) over a large volume (1 cm3). Those networks were validated as angiogenesis assays for pro- and anti-angiogenic compounds. LIST could be widely adapted for applications requiring multiscale bioprinting capabilities, like the development of 3D drug screening models and artificial tissues.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Sayadeh Sara Hosseini Kolkooh, Hamid Ebrahimi Orimi, Erika Hooker, Sivakumar Narayanswamy, Bruno Larrivee, and Christos Boutopoulos "Bioprinting 3D angiogenesis models with Laser Induced Side Transfer", Proc. SPIE 11647, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX, 116471D (5 March 2021); https://doi.org/10.1117/12.2584573
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
3D modeling
Capillaries
3D displays
Glasses
Laser applications
Laser energy
Printing
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top