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5 March 2021 Real-time biosensors for continuous measurements of specific biomolecules in vivo
Hyongsok T. Soh
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Proceedings Volume 11663, Integrated Sensors for Biological and Neural Sensing; 116630T (2021) https://doi.org/10.1117/12.2580234
Event: SPIE BiOS, 2021, Online Only
Abstract
In this presentation, we will present a general biosensor technology capable of continuously tracking a wide range of molecules in living subjects. Our real-time biosensor requires no exogenous reagents and can be readily reconfigured to measure different target molecules by exchanging molecular probes in a modular manner. Next, we will present the first real-time, closed loop feedback control of drug concentration in live animals using the real-time biosensor and discuss potential applications of our technology. Finally, we will discuss methods for generating synthetic molecular switches that are at the heart of the biosensor.
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Hyongsok T. Soh "Real-time biosensors for continuous measurements of specific biomolecules in vivo", Proc. SPIE 11663, Integrated Sensors for Biological and Neural Sensing, 116630T (5 March 2021); https://doi.org/10.1117/12.2580234
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KEYWORDS
Biosensors
In vivo imaging
Molecules
Feedback control
Glucose
Heart
Oxygen
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