Paper
18 June 2021 Optical and thermal interactions of different-wavelength ultrashort laser pulses with breast cancer based on COMSOL
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Proceedings Volume 11850, First Optics Frontier Conference; 1185007 (2021) https://doi.org/10.1117/12.2599023
Event: First Optics Frontier Conference, 2021, Hangzhou, China
Abstract
We use commercial finite element simulation software COMSOL Multiphysics to simulate the generation and propagation of photothermal signals. The software is based on the finite element method, solving actual physical phenomena, through mathematical methods to solve partial differential equations to simulate real physical phenomena. Its advantages mainly include excellent computing performance and multi-field coupling ability, accurate numerical simulation results, and good calculation for various physical phenomena in various fields of scientific research. In the visualization research of breast cancer photothermal imaging in this paper. We mainly simulate the generation and transmission of breast cancer photothermal effect through two modules: light transmission module and biological heat transfer module. We use the simulation software COMSOL Multiphysics to develop a computer numerical simulation model composed of water, tumor, breast tissue, subcutaneous tissue, epithelial tissue and short pulse laser sources of different wavelengths. The model studied the propagation and heat transfer of laser at 633nm, 700nm, 752nm and 900nm in the human breast. The energy transfer from the water layer to the breast tissue is described by the diffusion equation or the Helmholtz equation. The temperature change of the breast tumor and each breast tissue is obtained by solving the biological heat transfer equation. The interaction of the short pulse laser with the breast model at different wavelengths was obtained.
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Yuli Li, Ao Teng, Zihao Li, and Xianlin Song "Optical and thermal interactions of different-wavelength ultrashort laser pulses with breast cancer based on COMSOL", Proc. SPIE 11850, First Optics Frontier Conference, 1185007 (18 June 2021); https://doi.org/10.1117/12.2599023
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