Paper
1 July 2021 Biomaterials-based anti-traumatic and antibacterial gauze dressing pads for partial thickness wounds
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Proceedings Volume 11877, Second iiScience International Conference 2021: Recent Advances in Photonics and Physical Sciences; 1187702 (2021) https://doi.org/10.1117/12.2599866
Event: 2nd iiScience International Conference 2021: Recent Advances in Photonics and Physical Sciences, 2021, Faisalabad, Pakistan
Abstract
Wound care is as aged as the mankind. Different kind of woven and nonwoven dressings are being used for all types of burn wounds. Many of the researchers worked on the non-adherent dressings. Achieving the non-adhesiveness compromised on many other factors such as exudates absorption, leaching of paraffin oil/wax into the wound, healing process, and antibacterial properties etc. This research work fulfills almost all the gaps with low cost. Gauze dressings coated with paraffin oil were impregnated with different combination of sodium alginate, chitosan, PVA and honey. Besides this silver was also used to enhance the antibacterial properties. SEM was used to analyze the surface morphology before and after applying different biocompatible materials (alginate, PVA and chitosan) in combination with honey and silver salt. Comfort properties (stiffness and moisture management) and antibacterial efficacy of developed samples was evaluated by following the standard test methods. Independent t-test proved significant difference between the stiffness results depending on the drying method. But the t-test results showed that there was no significant difference of drying method on the overall moisture management capability (OMMC). All the developed gauze dressing pads (GDPs) showed good antibacterial against both gram positive (S. Aureus) and gram negative (E. Coli) bacterial strains, but the combination of chitosan, silver and honey has shown larger zone of inhibition for both strains. Thus, on the behalf of the antibacterial activity, stiffness, and moisture management the dressing with composition; chitosan+ silver+ honey can be the best choice for partial thickness burn wounds.
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Muhammad Anam Khubaib, Rashid Masood, Dominique Adolphe, Ahsan Nazir, and Muhammad Hassan Rafe "Biomaterials-based anti-traumatic and antibacterial gauze dressing pads for partial thickness wounds", Proc. SPIE 11877, Second iiScience International Conference 2021: Recent Advances in Photonics and Physical Sciences, 1187702 (1 July 2021); https://doi.org/10.1117/12.2599866
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