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Many skin and systemic diseases are accompanied by changes in the vessels of the skin. The role of the vascular component in the pathogenesis of diseases in most cases remains underestimated and is not sufficiently taken into account in the treatment. One of the reasons is the lack of safe, effective and accessible methods of objective assessment of skin vessels. The possibilities of the histological method are limited [1] due to vascular damage during biopsy and manufacture of the drug, as well as the inability to perform multi-focal and dynamic studies. Capillaroscopy and dermatoscopy also do not solve the problem, as they allow only indirectly to judge the condition of the skin vessels [2]. The possibilities of other non-invasive methods of examining skin vessels are being studied. One of the promising methods of lifetime examination of skin vessels is optical coherence tomography (OCT). This is a high-resolution (10-20 mk) method for visualizing the structure of biological tissues, using low-intensity near-infrared light as probing radiation [3]. The purpose of the work To study the possibilities of using OCT and 3D OCT to assess the state of the microcirculatory bed of the skin.
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K. S. Petrova, S. V. Nemirova, G. A. Petrova, A. A. Karpenko, M. G. Ryabkov, "Three-dimensional optical coherence tomography: possibilities in assessing the microvasculature of the skin," Proc. SPIE 11934, Photonics in Dermatology and Plastic Surgery 2022, 119340M (3 March 2022); https://doi.org/10.1117/12.2607875