Poster + Paper
4 April 2022 Anonymising pathology data using generative adversarial networks
David Morrison, David Harris-Birtill
Author Affiliations +
Conference Poster
Abstract
Anonymising medical data for use in machine learning is important to preserve patient privacy and, in many circumstances, is a requirement before data can be made available. One approach to anonymising image data is to train a generative model to produce data that is statistically similar to the input data and then use the output of the model for downstream tasks, such as image classification, instead of the original sensitive data. In digital pathology, it's not yet well understood how using generative models to anonymise histology slide data impacts the performance of downstream tasks. To begin addressing this, we present an evaluation of a histology image classifier trained using patches extracted from the Camelyon 16 dataset and compare it to a classifier trained on the same number of synthetic images generated with a Deep Convolutional Generative Adversarial Network (DCGAN), from the same data. When predicting the class of an image patch as either cancer or normal it's shown that the accuracy reduces from 0.78 for original alone to 0.59 for synthetic alone, and the recall is significantly reduced from 0.70 to 0.44 when training exclusively on the same amount of synthetic data. If retaining a similar accuracy is required for the downstream task, then either the original data must be used or an improved anonymisation strategy must be devised. We conclude that using this DCGAN to anonymise the dataset, degrades the accuracy of the classifier which implies that it has failed to capture the required variation in the original data to generalise and act as a sufficient anonymisation strategy.
© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
David Morrison and David Harris-Birtill "Anonymising pathology data using generative adversarial networks", Proc. SPIE 12039, Medical Imaging 2022: Digital and Computational Pathology, 1203917 (4 April 2022); https://doi.org/10.1117/12.2611803
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KEYWORDS
Data modeling

Pathology

Statistical modeling

Tissues

Cancer

Image classification

Medical imaging

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