Acoustic radiation force optical coherence elastography based on acousto-optic coupling for elasticity measurements

Chongyang Wang; Jiang Zhu; Fan Fan; Xiaochen Meng; Zongqing Ma

doi:10.1117/12.2641803

19 December 2022 Acoustic radiation force optical coherence elastography based on acousto-optic coupling for elasticity measurements

Chongyang Wang, Jiang Zhu, Fan Fan, Xiaochen Meng, Zongqing Ma

Author Affiliations +

Proceedings Volume 12320, Optics in Health Care and Biomedical Optics XII; 123201L (2022) https://doi.org/10.1117/12.2641803
Event: SPIE/COS Photonics Asia, 2022, Online Only

Conference Poster

Abstract

The elastic properties can be an indicator of pathological changes of biological tissue. Acoustic radiation force optical coherence elastography (ARF-OCE) allows remote, non-invasive assessment of the elastic properties of tissue. In this study, we proposed an acousto-optic coupling ARF-OCE method for the elasticity measurements. The acousto-optic coupling unit employs a rectangular prism with a close refractive index but significantly different acoustic impedance compared to water. Therefore, the surface of the rectangular prism immersed in water can reflect the ultrasound beam while transmitting the optical coherence tomography (OCT) detection beam. We demonstrated the acousto-optic coupling ARFOCE method using agar phantoms. The results show that the ARF-OCE method can induce elastic vibrations in the direction parallel to the OCT beam, resulting in higher detection sensitivity and a larger scanning range.

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Chongyang Wang, Jiang Zhu, Fan Fan, Xiaochen Meng, and Zongqing Ma "Acoustic radiation force optical coherence elastography based on acousto-optic coupling for elasticity measurements", Proc. SPIE 12320, Optics in Health Care and Biomedical Optics XII, 123201L (19 December 2022); https://doi.org/10.1117/12.2641803

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