Advances in the preparation and application of polymeric micelles

Zengyun Chen; Siya Deng; Lin Tian

doi:10.1117/12.2672920

25 April 2023 Advances in the preparation and application of polymeric micelles

Zengyun Chen, Siya Deng, Lin Tian

Proceedings Volume 12598, Eighth International Conference on Energy Materials and Electrical Engineering (ICEMEE 2022); 1259809 (2023) https://doi.org/10.1117/12.2672920
Event: Eighth International Conference on Energy Materials and Electrical Engineering (ICMEE 2022), 2022, Guangzhou, China

Abstract

Polymeric micelles are block or grafted copolymers formed by both hydrophobic and hydrophilic segments. Although polymeric micelles have been one of the research hotspots for the past decades, most of the results reported focus on their application as drug delivery vehicles, which are utilized to cure diseases accurately without obvious side effects. Few researchers have explored other types of applications. Therefore, there has been lack of summarized information to present a thorough overview of this type of high technology. In this review, starting with the definition of polymeric micelles and information such as typical shapes and morphology, synthesize approaches such as block arrangement, changing pH and temperature, bond interactions will be introduced. In fact, there are multiple ways to synthesize different types of polymeric micelles. For potential applications, their use as intracellular hypersensitive nanoprobes will be discussed. If designed properly, they could detect various kinds of bio signals and interact with pernicious ions to eliminate their underlying threats. Photo-responsive polymeric micelles will also be illustrated, which has appealed to many scholars and enterprises. 5 types of photo-responsive polymeric micelles will be introduced, which exhibit various photo-responsive mechanisms and impact of light on different functional groups. In the end, the future prospect of polymeric micelle will be predicted. Possible applications and challenges remained will be mentioned. This review hopes to offer inspiration to researchers in order to enlarge the application scope of polymeric micelles.

Citation Download Citation

Zengyun Chen, Siya Deng, and Lin Tian "Advances in the preparation and application of polymeric micelles", Proc. SPIE 12598, Eighth International Conference on Energy Materials and Electrical Engineering (ICEMEE 2022), 1259809 (25 April 2023); https://doi.org/10.1117/12.2672920

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