Paper
8 January 2024 Advances in esophageal cancer-specific tumor markers and immunotherapy
Yue Guo
Author Affiliations +
Proceedings Volume 12924, Third International Conference on Biological Engineering and Medical Science (ICBioMed2023); 129242H (2024) https://doi.org/10.1117/12.3012834
Event: 3rd International Conference on Biological Engineering and Medical Science (ICBioMed2023), 2023, ONLINE, United Kingdom
Abstract
Esophageal cancer has a high fatality rate among common cancers. There are no obvious symptoms in the early stage of esophageal cancer, leading to untimely diagnosis and disease progression. Therefore, finding the right tumor markers to improve diagnostic accuracy and enable early detection and treatment is particularly important to reduce mortality and improve quality of life for patients. Traditional treatments are surgery, radiotherapy and chemotherapy, but the treatment effect is usually poor. Immunotherapy for oncology, represented by immune checkpoint inhibitors (ICIs), has been on the rise in recent years and is beginning to take its place in the first, second and third lines of treatment for esophageal cancer. In this review, some more studied tumor markers including DNA methylation, expression of miRNA and lncRNA, exosomes, tumor microenvironment and circulating tumor cells are summarized, and some promising immunotherapies, some are corresponding with markers, are introduced, providing a reference for the diagnosis and treatment of esophageal cancer.
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yue Guo "Advances in esophageal cancer-specific tumor markers and immunotherapy", Proc. SPIE 12924, Third International Conference on Biological Engineering and Medical Science (ICBioMed2023), 129242H (8 January 2024); https://doi.org/10.1117/12.3012834
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KEYWORDS
Tumors

Cancer

Cancer detection

Diagnostics

Oncology

Therapeutics

Tumor growth modeling

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