Light penetration in human skin: in-vivo measurements using isotropic detector

Ivan S. Melnik; Rudolf W. Steiner; Alwin Kienle

doi:10.1117/12.146313

18 June 1993 Light penetration in human skin: in-vivo measurements using isotropic detector

Ivan S. Melnik, Rudolf W. Steiner, Alwin Kienle

Proceedings Volume 1881, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II; (1993) https://doi.org/10.1117/12.146313
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

An isotropic probe for direct measurement of fluence rate in tissue was made by melting 110 micrometers -core fiber to less than 0.4 mm sphere and painting by scattering material. Anisotropy response for the best probe of 0.35 mm diameter was +/- 10% in angular range to +/- 150 degree(s). The general position error of the probe in the tissue provided by experimental setup was less than 0.1 mm. The fluence rate was measured in the human leg in vivo at a depth of up to 5 mm for incident irradiance of 100 mW/cm² and wavelength 625 nm (dye laser) for beam diameters of 1 mm and 5 mm. Effective attenuation coefficients of about 0.6 mm^-1 (for depth of up to 1 mm) and 0.7 mm^-1 (for muscle layers) were obtained. Differences in light distribution in the skin comparative to the deeper layers were not found.

Citation Download Citation

Ivan S. Melnik, Rudolf W. Steiner, and Alwin Kienle "Light penetration in human skin: in-vivo measurements using isotropic detector", Proc. SPIE 1881, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II, (18 June 1993); https://doi.org/10.1117/12.146313

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