Randomized controlled trial comparing the effects of Nd:YAG prostate ablation with or without KTP laser bladder neck incision

Stephen Langley M.D.; Christopher Gallegos M.D.; Clifford Moisey M.D.

doi:10.1117/12.275071

22 May 1997 Randomized controlled trial comparing the effects of Nd:YAG prostate ablation with or without KTP laser bladder neck incision

Stephen Langley M.D., Christopher Gallegos M.D., Clifford Moisey M.D.

Author Affiliations +

Proceedings Volume 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII; (1997) https://doi.org/10.1117/12.275071
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

A randomized, double blind, power determined, prospective study compared patients with benign prostatic hyperplasia undergoing endoscopic laser ablation of prostate, ELAP, -- Group 1 -- to those with KTP bladder neck incision and ELAP -- Group 2. A dual wavelength Laserscope KPT/532TM laser was used with add/stat side-firing fibers. Post-operatively a urethral catheter was inserted, which was removed at 18 hours. Patients unable to void at this stage where then re-catheterized, discharged and readmitted two weeks later for catheter removal. Patients were followed up at three month intervals. Eighty eight patients were studied, pre-operatively there was no statistical difference between Group 1 and Group 2 in mean age, 68.0, 68.4 yrs; prostate size 28, 29 g; post void residual, PVR, 141, 126 ml; max flow rate, Qmax, 9.8, 9.4 ml/s; or AUA score 18.0, 20.4; respectively. Post-operatively 57% of Group 1 patients were able to void on catheter removal at 18 hours compared to 80% from Group 2; p less than 0.05, (chi) ². After one month, two patients from Group 2 and one from Group 1 failed to void and required further surgery. At six months, data for Group 1 and 2 respectively: PVR equals 78.7, 61.4 ml, Qmax equals 16.2, 18.1 ml/s, AUA score equals 9.6, 6.38, p less than 0.005 for each. Group 2 had a significantly greater improvement in AUA7 score than Group 1.

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Stephen Langley M.D., Christopher Gallegos M.D., and Clifford Moisey M.D. "Randomized controlled trial comparing the effects of Nd:YAG prostate ablation with or without KTP laser bladder neck incision", Proc. SPIE 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII, (22 May 1997); https://doi.org/10.1117/12.275071

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KEYWORDS

Bladder

Nd:YAG lasers

Neck

Ferroelectric materials

Prostate

Laser ablation

Surgery

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