Influence of laser irradiation on demyelination of nervous fibers

Nataly O. Melnik; Yu. S. Plaksij; Serge A. Mamilov

doi:10.1117/12.405913

3 November 2000 Influence of laser irradiation on demyelination of nervous fibers

Nataly O. Melnik, Yu. S. Plaksij, Serge A. Mamilov

Proceedings Volume 4159, Effects of Low-Power Light on Biological Systems V; (2000) https://doi.org/10.1117/12.405913
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Problem demyelinating diseases from actual in modern of neurology. Main disease of this group - multiple sclerosis, which morphological manifestation is the process demyelineation - disintegration of myelin, which covers axial cylinders of nervous filaments. The outcome of such damage is violation of realization of nervous impulses, dissonance of implement and coordination functions. Most typical the feature of a multiple sclerosis is origin of repeated remissions, which compact with indication remyelination. In development of disease the large role is played by modifications of immunological of a reactivity of an organism. The purpose of the title is development of new methods of treatment of a multiple sclerosis because of lasertherapy. For thsi purpose the influence of a laser exposure on demyelination and remyelination processes will be investigated, is investigated pathological fabrics at microscopic and submicroscopic levels. The study of proceses demyelination and remyelination will be conducted on experimental animals (rats), which are sick experimental allergic encephalomyelitis (EAE), that is the most adequate model of a multiple sclerosis. The patients' EAE animals will be subjected to treatment by a laser exposure. For want of it there will be determinate optimum lengths of waves, dozes and modes of laser radiation.

Citation Download Citation

Nataly O. Melnik, Yu. S. Plaksij, and Serge A. Mamilov "Influence of laser irradiation on demyelination of nervous fibers", Proc. SPIE 4159, Effects of Low-Power Light on Biological Systems V, (3 November 2000); https://doi.org/10.1117/12.405913

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