Proposed system for ultrasonic temperature imaging of the human prostate in vivo during transurethral microwave thermotherapy: data acquisition and initial experience

Aswin L. Hoffmann; Jean J.M.C.H. de la Rosette; Hessel Wijkstra

doi:10.1117/12.428240

30 May 2001 Proposed system for ultrasonic temperature imaging of the human prostate in vivo during transurethral microwave thermotherapy: data acquisition and initial experience

Aswin L. Hoffmann, Jean J.M.C.H. de la Rosette, Hessel Wijkstra

Author Affiliations +

Proceedings Volume 4325, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing; (2001) https://doi.org/10.1117/12.428240
Event: Medical Imaging 2001, 2001, San Diego, CA, United States

Abstract

The feasibility of using a minimally-invasive pulse-echo diagnostic ultrasound technique for estimation of the spatiotemporal temperature distribution in the human prostate in vivo during transurethral microwave thermotherapy (TUMT) was investigated. The tissue temperature distribution was estimated using a method which allows spatially resolved measurement of changes in time of flight. Backscattered ultrasound RF signals were acquired from a commercially-available 7.5 MHz transrectal imaging probe and processed to compute and image the apparent tissue internal displacement distribution. The temperature distribution was determined by exploiting an estimated initial sound speed distribution and an empirical relationship between temperature and ultrasound transmission speed. Results form an in-vitro phantom study showed a linear relationship between induced displacement and temperature for a limited temperature range. Initial results from an exploratory in-vivo study in patients undergoing TUMT showed substantial influence form tissue motion and deformation. Problems inherent to in-vivo data acquisition are discussed and potential solutions are proposed. Possible approaches to further improve the algorithm and to assess the ability of the system to estimate and monitor the intraprostatic temperature distribution during TUMT are presented.

Citation Download Citation

Aswin L. Hoffmann, Jean J.M.C.H. de la Rosette, and Hessel Wijkstra "Proposed system for ultrasonic temperature imaging of the human prostate in vivo during transurethral microwave thermotherapy: data acquisition and initial experience", Proc. SPIE 4325, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing, (30 May 2001); https://doi.org/10.1117/12.428240

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