Microfabrication of hydrogels for biomedical applications

Tianyue Yu; Federica Chiellini; Dirk Schmaljohan; Roberto Solaro; Christopher Kemper Ober

doi:10.1117/12.474288

24 July 2002 Microfabrication of hydrogels for biomedical applications

Tianyue Yu, Federica Chiellini, Dirk Schmaljohan, Roberto Solaro, Christopher Kemper Ober

Proceedings Volume 4690, Advances in Resist Technology and Processing XIX; (2002) https://doi.org/10.1117/12.474288
Event: SPIE's 27th Annual International Symposium on Microlithography, 2002, Santa Clara, California, United States

Abstract

Hydrogels have gained general acceptance as biocompatible materials and are the basis of many promising applications in tissue engineering, drug release formulations and biosensors. Polymer processing techniques that can generate miniature hydrogel microstructures are not only critical as scaffolds for tissue re-growth but also very effective for increasing the efficiency of drug delivery and biosensors. Our approach is to use both optical and soft lithographic methods to microfabricate hydrogels. In this paper, we describe a photolithographic process to pattern hydrogel materials and analyze factors influencing sensitivity and lateral resolution. The model system we are investigating is based on 2-hydroxyethyl methacrylate (HEMA), which is well known for its non-toxicity and its widespread use in the contact lens industry.

Citation Download Citation

Tianyue Yu, Federica Chiellini, Dirk Schmaljohan, Roberto Solaro, and Christopher Kemper Ober "Microfabrication of hydrogels for biomedical applications", Proc. SPIE 4690, Advances in Resist Technology and Processing XIX, (24 July 2002); https://doi.org/10.1117/12.474288

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available