Quantification of cross-sectional artery wall motion with IVUS image registration

Kevin D. Oakeson; Hui Zhu; Morton H. Friedman

doi:10.1117/12.536523

28 April 2004 Quantification of cross-sectional artery wall motion with IVUS image registration

Kevin D. Oakeson, Hui Zhu, Morton H. Friedman

Proceedings Volume 5373, Medical Imaging 2004: Ultrasonic Imaging and Signal Processing; (2004) https://doi.org/10.1117/12.536523
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

Atherosclerotic lesions have been shown to have different mechanical properties than the non-diseased artery. Calculating vessel wall strain from cross-sectional vessel wall motions allows for the measurement of local stiffness. In this paper, a robust method is developed to track cross-sectional displacements of an artery wall using two different intravascular ultrasound (IVUS) images acquired at two different pressure levels respectively. First, the vessel wall region in one image is segmented semi-automatically by refining two spline-based contours to the locations of inner and outer vessel wall borders. Then the ringlike wall region in one image is registered to its counterpart in the other image in polar coordinates. The registration is performed by minimizing an energy function of the 2D motion field based on a spline-deformable-model. Both intensity and gradient information of the images are used to construct the energy function so that an accurate registration can be achieved. Registration accuracy was tested on simulated motions using IVUS images of a human coronary artery and a porcine carotid. The wall displacement fields calculated from real motion images are also demonstrated.

Citation Download Citation

Kevin D. Oakeson, Hui Zhu, and Morton H. Friedman "Quantification of cross-sectional artery wall motion with IVUS image registration", Proc. SPIE 5373, Medical Imaging 2004: Ultrasonic Imaging and Signal Processing, (28 April 2004); https://doi.org/10.1117/12.536523

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