Nanosensor for detection of glucose

Ignacio Del Villar; Ignacio R. Matias; Francisco J. Arregui

doi:10.1117/12.566547

9 June 2004 Nanosensor for detection of glucose

Ignacio Del Villar, Ignacio R. Matias, Francisco J. Arregui

Proceedings Volume 5502, Second European Workshop on Optical Fibre Sensors; (2004) https://doi.org/10.1117/12.566547
Event: Second European Workshop on Optical Fibre Sensors, 2004, Santander, Spain

Abstract

A novel fiber-optic sensor sensitive to glucose has been designed based on electrostatic self-assembly method. The polycation of the structure is a mixture of poly(allylamine hydrochloride) (PAH) and Prussian Blue, whereas the polyanion is well-known enzyme gluocose oxidase (GOx). The range of glucose concentration that can be measured is submilimolar and is located between 0.1 and 2 mM. Measures are based on a new detection scheme based on the slope of the change of signal produced by injection of glucose, yielding to a linear response. The sensor responses in a PH range between 4 and 7.4, which includes the physiological PH of blood. Some rules for esitmation of the refractive index of the material deposited and the thickness of bilayers are also given.

Citation Download Citation

Ignacio Del Villar, Ignacio R. Matias, and Francisco J. Arregui "Nanosensor for detection of glucose", Proc. SPIE 5502, Second European Workshop on Optical Fibre Sensors, (9 June 2004); https://doi.org/10.1117/12.566547

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