Discrimination of normal and colorectal cancer using Raman spectroscopy and fluorescence

Xiaozhou Li; Deli Wang; Yue Wang

doi:10.1117/12.727994

13 July 2007 Discrimination of normal and colorectal cancer using Raman spectroscopy and fluorescence

Xiaozhou Li, Deli Wang, Yue Wang

Proceedings Volume 6633, Biophotonics 2007: Optics in Life Science; 66331P (2007) https://doi.org/10.1117/12.727994
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

Laser-induced fluorescence spectroscopy (LIF) and Raman spectrum of serum for diagnosis of colon cancer and rectum cancer were investigated in this paper. The aim of this study was that using Raman spectrum and LIF analysis the serum of colon cancer and rectum cancer for found the difference compared to normal, the difference was found. For example: the intensity and red shift both different In this paper we investigated 82 colon cancers, 69 rectum cancers and obtained 80.7%, 82.5% accuracy to rectum cancer and colon cancer separately compared to clinical diagnostic. It is exploring that use Raman spectrum and LIF to detection of cancer.

Citation Download Citation

Xiaozhou Li, Deli Wang, and Yue Wang "Discrimination of normal and colorectal cancer using Raman spectroscopy and fluorescence", Proc. SPIE 6633, Biophotonics 2007: Optics in Life Science, 66331P (13 July 2007); https://doi.org/10.1117/12.727994

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