Extracting information from optical coherence tomography images of tissues: signal attenuation and fractal analysis of speckle pattern

Dan P. Popescu; Costel Flueraru; Youxin Mao; Shoude Chang; Michael G. Sowa

doi:10.1117/12.839791

22 February 2010 Extracting information from optical coherence tomography images of tissues: signal attenuation and fractal analysis of speckle pattern

Dan P. Popescu, Costel Flueraru, Youxin Mao, Shoude Chang, Michael G. Sowa

Author Affiliations +

Proceedings Volume 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII; 75550C (2010) https://doi.org/10.1117/12.839791
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Two methods for analyzing OCT images of arterial tissues are tested. These methods are applied toward two types of samples: segments of arteries collected from atherosclerosis-prone Watanabe heritable hyper-lipidemic rabbits and pieces of porcine left descending coronary arteries without atherosclerosis. The first method is based on finding the attenuation coefficients for the OCT signal that propagates through various regions of the tissue. The second method involves calculating the fractal dimensions of the OCT signal textures in the regions of interest identified within the acquired images. A box-counting algorithm is used for calculating the fractal dimensions. Both parameters, the attenuation coefficient as well as the fractal dimension correlate very well with the anatomical features of both types of samples.

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Dan P. Popescu, Costel Flueraru, Youxin Mao, Shoude Chang, and Michael G. Sowa "Extracting information from optical coherence tomography images of tissues: signal attenuation and fractal analysis of speckle pattern", Proc. SPIE 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII, 75550C (22 February 2010); https://doi.org/10.1117/12.839791

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KEYWORDS

Optical coherence tomography

Signal attenuation

Fractal analysis

Tissues

Arteries

Blood circulation

Signal detection

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