Monte Carlo modeling for photoacoustic-based transport-regime optical property estimation

Janaka C. Ranasinghesagara; Roger J. Zemp

doi:10.1117/12.842038

23 February 2010 Monte Carlo modeling for photoacoustic-based transport-regime optical property estimation

Janaka C. Ranasinghesagara, Roger J. Zemp

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 75640F (2010) https://doi.org/10.1117/12.842038
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We developed a unique reflection-mode photoacoustic technique sensitive to optical scattering in turbid media. We focused a small laser spot on to the surface of a turbid medium and captured the photoacoustic signal by a focused ultrasound transducer. The amplitude of the photoacoustic signal for different surface illumination spot locations is an effective estimate of the Green's function of light transport in turbid media. Our results for different concentrations of Intralipid indicate that this method is capable of distinguishing small changes in the reduced scattering coefficient. In this work, we present experimental measurements for an Intralipid phantom with reduced scattering coefficients of 3, 4, and 5 cm^-1, and show that Monte Carlo simulations of light transport accurately reproduce experimental curves. This means that we can estimate transport-regime optical properties of the media given a suitable fitting algorithm.

Citation Download Citation

Janaka C. Ranasinghesagara and Roger J. Zemp "Monte Carlo modeling for photoacoustic-based transport-regime optical property estimation", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75640F (23 February 2010); https://doi.org/10.1117/12.842038

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KEYWORDS

Photoacoustic spectroscopy

Optical properties

Scattering

Tissue optics

Light scattering

Monte Carlo methods

Inverse optics

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