Photonically enhanced polymer labs-on-a-chip

H. Ottevaere; J. Van Erps; M. Vervaeke; H. Thienpont

doi:10.1117/12.928152

8 May 2012 Photonically enhanced polymer labs-on-a-chip

H. Ottevaere, J. Van Erps, M. Vervaeke, H. Thienpont

Proceedings Volume 8428, Micro-Optics 2012; 84280Z (2012) https://doi.org/10.1117/12.928152
Event: SPIE Photonics Europe, 2012, Brussels, Belgium

Abstract

We present micro-optical detection units for both laser-induced fluorescence and absorbance analysis. The detection systems are designed by means of non-sequential ray tracing simulations and prototyped by means of deep proton writing. In a proof-of-concept demonstration, the micro-optical unit is used for the detection of various concentrations of coumarin dyes. Several measures to increase the signal-to-noise ratio, such as automation of the sample injection, improved suppression of environmental stray light, usage of optimal detectors and simple yet effective post-processing of the raw detection signals are implemented, resulting in a concentration measurement range for fluorescence from 6pM up to 0.6mM and for absorbance from 0.6μM to 12mM. The wide measurement range and the possibility of using standard fabrication techniques to prototype and replicate this miniaturized plastic system, make it a good candidate for applications where small samples need to be characterized optically with a low-cost and portable system.

Citation Download Citation

H. Ottevaere, J. Van Erps, M. Vervaeke, and H. Thienpont "Photonically enhanced polymer labs-on-a-chip", Proc. SPIE 8428, Micro-Optics 2012, 84280Z (8 May 2012); https://doi.org/10.1117/12.928152

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