Ultrasound perfusion signal processing for tumor detection

MinWoo Kim; Craig K. Abbey; Michael F. Insana

doi:10.1117/12.2214345

1 April 2016 Ultrasound perfusion signal processing for tumor detection

MinWoo Kim, Craig K. Abbey, Michael F. Insana

Proceedings Volume 9790, Medical Imaging 2016: Ultrasonic Imaging and Tomography; 97900O (2016) https://doi.org/10.1117/12.2214345
Event: SPIE Medical Imaging, 2016, San Diego, California, United States

Abstract

Enhanced blood perfusion in a tissue mass is an indication of neo-vascularity and a sign of a potential malignancy. Ultrasonic pulsed-Doppler imaging is a preferred modality for noninvasive monitoring of blood flow. However, the weak blood echoes and disorganized slow flow make it difficult to detect perfusion using standard methods without the expense and risk of contrast enhancement. Our research measures the efficiency of conventional power-Doppler (PD) methods at discriminating flow states by comparing measurement performance to that of an ideal discriminator. ROC analysis applied to the experimental results shows that power Doppler methods are just 30-50 % efficient at perfusion flows less than 1ml/min, suggesting an opportunity to improve perfusion assessment through signal processing. A new perfusion estimator is proposed by extending the statistical discriminator approach. We show that 2-D perfusion color imaging may be enhanced using this approach.

Citation Download Citation

MinWoo Kim, Craig K. Abbey, and Michael F. Insana "Ultrasound perfusion signal processing for tumor detection", Proc. SPIE 9790, Medical Imaging 2016: Ultrasonic Imaging and Tomography, 97900O (1 April 2016); https://doi.org/10.1117/12.2214345

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