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In this work, we compare the accuracy of radiological axial imaging-guided surgical navigation (computed tomography (CT) and magnetic resonance (MR)) with and without the use of subsurface fluorescence guidance. We tested this by utilizing a validated tissue-simulating phantom model of various tissue types with a randomly placed tumor inclusion and then dissecting the phantoms using different combinations of navigation modalities. Results demonstrated that fluorescence guidance improves the accuracy of radiological imaging-guided surgery with significant improvements in margin consistency and tumor inclusion alignment.
Kendra A. Hebert andEric R. Henderson
"Fluorescence guidance enhances the accuracy of radiological imaging-guided surgical navigation", Proc. SPIE PC11943, Molecular-Guided Surgery: Molecules, Devices, and Applications VIII, PC119430A (7 March 2022); https://doi.org/10.1117/12.2610224
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Kendra A. Hebert, Eric R. Henderson, "Fluorescence guidance enhances the accuracy of radiological imaging-guided surgical navigation," Proc. SPIE PC11943, Molecular-Guided Surgery: Molecules, Devices, and Applications VIII, PC119430A (7 March 2022); https://doi.org/10.1117/12.2610224