A new approach to quantitative SERS with high enhancement

Samir Adhikari; Minjun Kim; Jong-Min Lee; Yudong Jang; Ilsun Yoon; Donghan Lee

doi:10.1117/12.2618226

3 March 2022 A new approach to quantitative SERS with high enhancement

Samir Adhikari, Minjun Kim, Jong-Min Lee, Yudong Jang, Ilsun Yoon, Donghan Lee

Proceedings Volume PC11978, Plasmonics in Biology and Medicine XIX; PC1197809 (2022) https://doi.org/10.1117/12.2618226
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

SERS has been actively researched due to its powerful label-free sensing mechanism. However, SERS sensors, although sensitive and powerful, are still not reproducible and not uniform for practical adoption. Our unique approach to SERS sensors satisfies all the sought-after characteristics: a SERS substrate that is uniform, reproducible, sensitive, large, and cost-effective. Specifically, we achieve a sensing uniformity of 4.2% averaged over 4 points and 2.3% over 16 points throughout the entire 6” substrate, and a SERS enhancement of 4.6 x 10^8. SERS spectra from four DNA bases are measured and their corresponding peaks are well defined down to 10 pM concentration.

Conference Presentation

Citation Download Citation

Samir Adhikari, Minjun Kim, Jong-Min Lee, Yudong Jang, Ilsun Yoon, and Donghan Lee "A new approach to quantitative SERS with high enhancement", Proc. SPIE PC11978, Plasmonics in Biology and Medicine XIX, PC1197809 (3 March 2022); https://doi.org/10.1117/12.2618226

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