Blue light cystoscopy (BLC) has been demonstrated to detect bladder tumors with better sensitivity than white light cystoscopy (WLC); however, the use of BLC is limited to the operating room. In this study, we aim to bring BLC to the clinic by transforming WLC frames into digitally-stained BLC-like frames. We collected region-matched WLC and BLC videos from TURBT procedures and generated BLC-like frames, using WLC frames as input and the matched BLC frames as target. We will discuss the staining performances with perfectly registered WLC-BLC datasets, as well as WLC and BLC video clips collected with commercial clinical systems.
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