Dr. Lingyun Chen Profile

Dr. Lingyun Chen

Postdoctoral Fellow at Univ of Texas MD Anderson Cancer Ctr

SPIE Involvement:

Author

Publications (18)

Proceedings Article | 23 March 2010 Paper

Detection of simulated microcalcifications in digital mammography: effects of quantum and anatomic noises: preliminary study

Chao-Jen Lai, Xinming Liu, Zhicheng You, Youtao Shen, Yuncheng Zhong, Lingyun Chen, Tao Han, Shuaiping Ge, Ying Yi, William Geiser, David Flores, Gary Whitman, Wei Yang, Chris Shaw

Proceedings Volume 7622, 76224Y (2010) https://doi.org/10.1117/12.844426

KEYWORDS: Breast, Digital mammography, Signal to noise ratio, Mammography, LCDs, Visibility, X-rays, Target acquisition, Tissues, Image processing

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Proceedings Article | 23 March 2010 Paper

Images registration and superimposition for dual resolution cone beam CT: a preliminary study

Zhicheng You, Youtao Shen, Yuncheng Zhong, Lingyun Chen, Tao Han, Shuaiping Ge, Ying Yi, Tianpeng Wang, Chao-Jen Lai, Xinming Liu, Chris Shaw

Proceedings Volume 7622, 762234 (2010) https://doi.org/10.1117/12.844450

KEYWORDS: Image resolution, Breast, Sensors, Image registration, Aluminum, Computed tomography, X-ray computed tomography, Reconstruction algorithms, Breast cancer, X-rays

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Proceedings Article | 23 March 2010 Paper

Demonstration of dual resolution cone beam CT technique with an a-Si/a-Se flat panel detector

Youtao Shen, Yuncheng Zhong, Lingyun Chen, Chao-Jen Lai, Xinming Liu, Tao Han, Ying Yi, Zhicheng You, Shuaiping Ge, Tianpeng Wang, Chris Shaw

Proceedings Volume 7622, 76223B (2010) https://doi.org/10.1117/12.844423

KEYWORDS: Image resolution, Breast, Sensors, Aluminum, X-ray computed tomography, Breast cancer, X-rays, Reconstruction algorithms, Image quality, Mammography

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Proceedings Article | 14 March 2009 Paper

Calcification visibility study using combined high dose and low dose cone beam CT projections

Y, Zhong, C. Lai, L. Chen, T. Han, Y. Shen, X. Liu, T. Wang, S. Ge, Y. Yi, Z. You, C. Shaw

Proceedings Volume 7258, 72585U (2009) https://doi.org/10.1117/12.813780

KEYWORDS: Visibility, Breast, 3D image processing, X-ray computed tomography, Computed tomography, Reconstruction algorithms, Calcium, Gaussian filters, Physics, X-rays

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Proceedings Article | 11 March 2009 Paper

Visibility of microcalcifications in CCD-based cone beam CT: a preliminary study

Youtao Shen, Lingyun Chen, Shuaiping Ge, Ying Yi, Tao Han, Yuncheng Zhong, Chao-Jen Lai, Xinming Liu, Tianpeng Wang, Chris Shaw

Proceedings Volume 7258, 72580M (2009) https://doi.org/10.1117/12.813806

KEYWORDS: Visibility, Signal to noise ratio, Breast, Charge-coupled devices, Sensors, CCD cameras, CCD image sensors, Imaging systems, Computed tomography, Breast cancer

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Proceedings Article | 11 March 2009 Paper

Volume and tissue composition preserving deformation of breast CT images to simulate breast compression in mammographic imaging

Tao Han, Lingyun Chen, Chao-Jen Lai, Xinming Liu, Youtao Shen, Yuncheng Zhong, Shuaiping Ge, Ying Yi, Tianpeng Wang, Chris Shaw

Proceedings Volume 7258, 72580K (2009) https://doi.org/10.1117/12.813813

KEYWORDS: Breast, Image segmentation, Mammography, Tissues, Image compression, Imaging systems, 3D modeling, X-ray computed tomography, Computed tomography, X-rays

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Proceedings Article | 11 March 2009 Paper

Breast density measurement: 3D cone beam computed tomography (CBCT) images versus 2D digital mammograms

Tao Han, Chao-Jen Lai, Lingyun Chen, Xinming Liu, Youtao Shen, Yuncheng Zhong, Shuaiping Ge, Ying Yi, Tianpeng Wang, Wei Yang, Chris Shaw

Proceedings Volume 7258, 72580L (2009) https://doi.org/10.1117/12.813823

KEYWORDS: Breast, Image segmentation, Tissues, Mammography, 3D image processing, Computed tomography, Breast cancer, 3D metrology, Radiology, Sensors

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Proceedings Article | 19 March 2008 Paper

Dose saving and scatter reduction in volume-of-interest (VOI) cone beam CT: work in progress

Chao-Jen Lai, Chris Shaw, Lingyun Chen, Xinming Liu, Tao Han, Tianpeng Wang

Proceedings Volume 6913, 69134V (2008) https://doi.org/10.1117/12.772807

KEYWORDS: Breast, Sensors, X-rays, Image quality, X-ray computed tomography, Optical filters, Lead, Image filtering, X-ray detectors, Mammography

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Proceedings Article | 19 March 2008 Paper

Comparison of the performances between anti-scatter grid and slot scanning technique for digital chest radiography: effect of anatomical background

Chao-Jen Lai, Chris Shaw, Xinming Liu, Lingyun Chen, Tao Han, Tianpeng Wang

Proceedings Volume 6913, 69134T (2008) https://doi.org/10.1117/12.771687

KEYWORDS: Radiography, Chest, X-rays, Seaborgium, X-ray imaging, Sensors, Signal attenuation, Chromium, Chest imaging, X-ray detectors

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Proceedings Article | 18 March 2008 Paper

Feasibility of dual-resolution cone beam breast CT: a simulation study

Lingyun Chen, Chris Shaw, Chao-Jen Lai, Tao Han, Xinming Liu, Tianpeng Wang

Proceedings Volume 6913, 69131E (2008) https://doi.org/10.1117/12.772288

KEYWORDS: Sensors, Breast, Image resolution, X-rays, X-ray computed tomography, Monte Carlo methods, X-ray detectors, Spatial resolution, Computed tomography, 3D image processing

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The feasibility of using the dual-resolution cone beam breast CT technique to obtain high-resolution images inside a selected volume-of-interest (VOI). The spatial resolution improvement, dose saving and scatter reduction with this technique are studied and demonstrated with simulations. With the dual-resolution cone beam CT technique, the breast is first scanned with a low resolution detector at a lower exposure level. A selected volume-of-interest (VOI) in the breast is then scanned with a small field, high-resolution detector at a higher exposure level. The two image sets are then combined together to reconstruct high-resolution 3-D images for the VOI. The spatial resolution that can be achieved was estimated by obtaining 3-D images of point objects and use them to compute the MTFs for evaluation as a function of the geometric magnification, detector blurring function and focal spot size. Monte Carlo simulation based on the Geant4 package was used to estimate the degree of dose saving and scatter reduction for a cylinder shaped breast phantom. The VOI images generated with the dual-resolution cone beam CT technique demonstrated the same visibility of micro-calcifications as those generated with the full-breast, high resolution image acquisition. It has been shown that the spatial resolution can be increased by factor of 1.2 with smaller focal spot size and larger magnification. With the exposure level outside the VOI reduced by a factor of 15, scatter components can be reduced by a factor of 5.5 or greater in and outside the VOI. Dose can be reduced by a factor of 5.5 inside the VOI and up to 20 outside the VOI. We have demonstrated that high spatial resolution inside the VOI may be achieved with a high-resolution detector (e.g. CCD/CsI), reduced focal spot size (0.3 mm), and optimized geometrical magnification (e.g.1.63). Exposure reduction outside the VOI has been shown to reduce the scatter components in the high-resolution projection image data for the VOI. This has also led to significantly lowered doses inside and outside the VOI.

Proceedings Article | 18 March 2008 Paper

Simulation of mammograms and tomosynthesis imaging with cone beam breast CT images

Tao Han, Chris Shaw, Lingyun Chen, Chao-jen Lai, Xinming Liu, Tianpeng Wang

Proceedings Volume 6913, 691317 (2008) https://doi.org/10.1117/12.772944

KEYWORDS: Breast, X-ray computed tomography, Mammography, X-rays, Optical simulations, Tissues, Sensors, Computer simulations, X-ray imaging, Breast cancer

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