Amphetamines are a class of substances with a stimulating effect on the central nervous system. These were first synthesided in 1887 by Lazãr Edeleanu, a romanian chemist, in Germany, originally named phenylisopropylamine, but the stimulant effect of these was unknown until 1927, than it was resynthesized by Gordon Allens, who reported the sympathomimetic properties of amphetamines [1]. Urine amphetamine measurements were performed on the Viva-ProE analyzer (SIEMENS, Germany). The light source is a 12V-20W iodine quartz lamp. The range of scannable wavelengths with its own selection of 8 filters is as follows (340, 415, 505, 546, 570, 600, 660, 700 nm). The bandwidth is 8 - 12 nm. Photometric domain - Absorbance - 0.1 to 3.0. The authors present the results obtained by analyzing the urine samples from patients admitted in ICU II Toxicology with abuse substances overdose and working parameters of the Viva Pro-E System. Some of the results are presented. This analysis uses a threshold level of 300 ng / mL to distinguish positive and negative samples. The analysis provides only a preliminary analytical test result. A sample giving a change in the absorbance value (ΔA) equal to or even higher than the ΔA value of the Level 1 calibrator is interpreted as positive and the sample contains amphetamines or similar structural compounds or both.
Of all platinum metals, platinum has the most uses and it’s the most abundant and most easily to be processed. Its use in auto catalysts results in environmental contamination of crowded cities and high-traffic roads. In medicine, Pt is used as a cytostatic drug. In order to study the degree of contamination of the population with Pt or the correctness of treatment with Pt, it has been developed a method for its determination from urine or blood samples with a system Graphite Furnance - Atomic Absorption Spectrometer, (GF-AAS) Varian. There are presented the methods of sampling processing for blood or urine that followed the digest of the organic matrix. In the determination of the operating parameters for the system GF-AAS, was aimed the reducing of the nonanatomic absorbance by optimizing the drying temperatures, the calcination and atomization temperatures and the removal of the nonanatomic absorbance with D2 lamp. As a result of the use of the method are presented the concentrations of Pt in the blood or urine of a group of patients in Bucharest, a city with heavy traffic of vehicles. GF-AAS method presented is sensitive, reproducible, and relatively easy to apply with an acceptable cost. With this method, the concentration of Pt can be determined from blood and urine, both in order to establish the degree of contamination with Pt and for monitoring cancer therapy with platinum compounds.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.