Dual-modality photoacoustic/ultrasonic endoscopy has shown to be effective in the identification and staging of colorectal intramural tumors. In this study, we proposed a dual-modality endoscope with a spherical hollow PVDF-based transducer, which achieves center frequency of 34 MHz and -6 dB bandwidth of 15-60 MHz. The PVDF-based transducer will enable the system to achieve a large radial imaging range of more than 1 cm. In vivo imaging of the rabbit rectum proved that the dual-modality endoscope has the ability to perform the tissue stratification of the intestinal wall and the high-resolution visualization of the intestinal wall vascular network.
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