Owing to a red-shifted absorption/scattering feature compared to conventional plasmonic metals, titanium nitride nanoparticles (TiN NPs) constitute a promising candidate for nanomedicine. However, their potential is still underexplored due to difficulties of synthesis of stable biocompatible colloids of TiN NPs. Here, we provide results of elaboration of laser-ablative synthesis of TiN NPs in liquids which can solve the problem. Laser-ablated TiN NPs have strong plasmonic peak in near-IR. We also present their first comprehensive biocompatibility assessment. The obtained results evidence high safety of laser-synthesized TiN NPs for biological systems, which promises a major advancement of phototheranostic modalities on their basis.
We present phase-responding Fourier nanotransducers based on plasmonic metamaterials for ultrasensitive control of
dynamic characteristics of 2D materials and functional biosensing interfaces. These nanotransducers are designed in such
a way that they can confine light in 2D plane contacting with a probed ultrathin sample, gathering information about its
properties, and then transmitting the information into discrete optical beams with amplified phase relations. To demonstrate
their potential of Fourier transducers in biosensing, we designed Fourier nanotransducers based on periodic gold
nanostructures and applied it in a newly developed protocol for the detection of important antibiotic chloramphenicol
(CAP). Such biosensing tests showed the lower detection limit at fg mL−1 level, which several orders of magnitude better
than reported in the literature. The implementation of Fourier nanotransducers opens new opportunities for a radical
improvement of current state-of-the art plasmonic biosensing technology.
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