To obtain uniform power distribution on the ATR prism for biomedical spectroscopy system, the power intensity mapping on the prism is precisely measured by using a newly developed probing technique. It is found that the distribution of QCL based system is less uniform than that of the FT-IR based system due to the high coherency of the laser beam. To homogenize the distribution, a lens is introduced to diffuse the light and the incident beam is inclined to increase the number of reflections in the prism. As a result, we confirmed that the measurement error of in-vivo experiments is suppressed.
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