Experimental study of myocardial revascularization by CO2 laser

Mingying Wu; Gongsong Li; Junheng Li M.D.

doi:10.1117/12.137040

5 March 1993 Experimental study of myocardial revascularization by CO₂ laser

Mingying Wu, Gongsong Li, Junheng Li M.D.

Proceedings Volume 1616, International Conference on Photodynamic Therapy and Laser Medicine; (1993) https://doi.org/10.1117/12.137040
Event: International Conference on Photodynamic Therapy and Laser Medicine, 1991, Beijing, China

Abstract

The coronary lesions are usually diffuse, so bypass and PTCA are indicated in only a limited proportion of coronary patients. Revascularization with laser was studied in our laboratory. Fifteen dogs with mimic myocardial ischemia by multiple coronary artery ligation were divided into two groups, five acting as a control group. In 10, CO₂ laser was adopted in making a series of channels in the myocardium. We aimed to evaluate the effect of laser in revascularization, and to document long-term follow up. Our experiment demonstrated that laser-producing channels protect myocardium from ischemic events. Postoperative improvement of ventricular function and increased regional myocardial perfusion were observed. Microscopic and SEM examination at intervals of 3 days to 3 months showed the patency of channels and development of collateral circulation.

Citation Download Citation

Mingying Wu, Gongsong Li, and Junheng Li M.D. "Experimental study of myocardial revascularization by CO₂ laser", Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); https://doi.org/10.1117/12.137040

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