CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12358 > Article
Presentation
17 March 2023 Dual near-infrared II laser modulates the cellular redox state of T cells and augments the efficacy of cancer immunotherapy
Shinya Yokomizo, Wataru Katagiri, Takanobu Ishizuka, Keiko Yamashita, Satoshi Kashiwagi
Author Affiliations +
Proceedings Volume PC12358, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2023; PC1235808 (2023) https://doi.org/10.1117/12.2656197
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Although immunotherapy, including immune checkpoint inhibitors, has revolutionized cancer treatment, only a small percentage of patients show sustained response. Recently, we have shown that photobiomodulation (PBM) with near-infrared (NIR) light in the NIR-II window reduces oxidative stress and supports CD8+ T cell proliferation, suggesting that PBM with NIR-II light may enhance anticancer immunity. In this study, we report a novel approach to support tumor-infiltrating CD8+ T cells by PBM using NIR-II laser with high tissue penetration depth. Lasers are a safe and low-cost therapy that can be used in combination with a broad range of other therapies without modification.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Shinya Yokomizo, Wataru Katagiri, Takanobu Ishizuka, Keiko Yamashita, and Satoshi Kashiwagi "Dual near-infrared II laser modulates the cellular redox state of T cells and augments the efficacy of cancer immunotherapy", Proc. SPIE PC12358, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2023, PC1235808 (17 March 2023); https://doi.org/10.1117/12.2656197
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Cancer
Modulation
Tumors
Laser development
Therapeutics
Laser tissue interaction
Near infrared
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top