Prof. Ryan K. Roeder
Professor at Univ of Notre Dame
SPIE Involvement:
Author
Area of Expertise:
biomaterials , nanoparticles , computed tomography , photon-counting spectral computed tomography , radiographic contrast agents , tissue engineering scaffolds
Profile Summary

Ryan K. Roeder earned B.S. and Ph.D. degrees in Materials Engineering from Purdue University in 1994 and 1999, respectively, and then completed a two year post-doctoral research appointment in the Department of Orthopaedic Surgery at the Indiana University Medical Center. Ryan is currently a Professor in the Department of Aerospace and Mechanical Engineering and Bioengineering Graduate Program at the University of Notre Dame, where he was initially appointed in 2001. His research interests broadly span biomaterials, including nanoparticles for imaging probes and drug delivery and scaffolds for regenerating tissues; biomechanics, including the mechanobiology and micromechanics of musculoskeletal tissues; and biomedical imaging, including photon-counting spectral computed tomography. Recent research has focused on targeted nanoparticle probes for contrast-enhanced computed tomography (CT). Laboratory expertise includes nanoparticle synthesis, surface functionalization, and characterization; in vitro and in vivo models for targeted delivery, especially in cancer; and various CT imaging techniques (contrast-enhanced, dual-energy, spectral). Ryan has trained 3 postdocs and 17 doctoral students who have subsequently achieved their own success in research positions at universities, research hospitals, private research institutes, and industry. Ryan’s research has been supported by federal agencies (e.g., NIH, NSF, CDMRP PRMRP), industrial sponsors, and private foundations, as well as by a number of local, regional and international collaborations.
Publications (5)

Proceedings Article | 4 April 2022 Poster + Paper
Proceedings Volume 12031, 120312Y (2022) https://doi.org/10.1117/12.2611828
KEYWORDS: Gadolinium, Image denoising, Calcium, Iodine, Spatial resolution, Tissues, Image quality, Image classification, Spectral computed tomography, X-ray computed tomography, X-ray medical imaging

SPIE Journal Paper | 11 February 2019
Tyler Curtis, Ryan Roeder
JMI, Vol. 6, Issue 01, 013501, (February 2019) https://doi.org/10.1117/12.10.1117/1.JMI.6.1.013501
KEYWORDS: Gadolinium, Calcium, Iodine, Signal attenuation, Calibration, Tissue optics, X-rays, X-ray computed tomography, Sensors, Tissues

Proceedings Article | 9 March 2017 Presentation + Paper
Ryan Roeder, Tyler Curtis, Prakash Nallathamby, Lisa Irimata, Tracie McGinnity, Lisa Cole, Tracy Vargo-Gogola, Karen Cowden Dahl
Proceedings Volume 10132, 101320X (2017) https://doi.org/10.1117/12.2255688
KEYWORDS: Nanoparticles, X-ray computed tomography, Molecular imaging, Cancer, Gold, Computed tomography, Multimodal imaging, Nano contrast agents, Photon counting, Breast, Tumors, Target detection

Proceedings Article | 9 March 2017 Paper
Tyler Curtis, Ryan Roeder
Proceedings Volume 10132, 101323L (2017) https://doi.org/10.1117/12.2255661
KEYWORDS: Calibration, Photon counting, Computed tomography, Sensors, Gadolinium, Signal attenuation, X-ray computed tomography, Image segmentation, X-rays, Diagnostics

Proceedings Article | 16 February 2017 Paper
Proceedings Volume 10100, 101001G (2017) https://doi.org/10.1117/12.2252844
KEYWORDS: Raman spectroscopy, Phonons, Nanoparticles, Polaritons, Reflection, Hybrid fiber optics, Thin films, Gold, Crystals, Dielectrics

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