The different lengths and conduction velocities of axons connecting cortical regions of the brain yield information transmission delays which are believed to be fundamental to brain dynamics. A critical step in the estimation of axon conduction speed in vivo is the estimation of the inter hemispheric transfer time (IHTT). The IHTT is estimated using electroencephalography (EEG) by measuring the latency between the peaks of specific electrodes or by computing the lag to maximum correlation on contra lateral electrodes. These approaches do not take the subject’s anatomy into account and, due to the limited number of electrodes used, only partially leverage the information provided by EEG. Using the previous published Connectivity Informed Maximum Entropy on the Mean (CIMEM) method, we propose a new approach to estimate the IHTT. In CIMEM, a Bayesian network is built using the structural connectivity information between cortical regions. EEG signals are then used as evidence into this network to compute the posterior probability of a connection being active at a particular time. Here, we propose a new quantity which measures how much of the EEG signals are supported by connections, which is maximized when the correct conduction delays are used. Using simulations, we show that CIMEM provides a more accurate estimation of the IHTT compared to the peak latency and lag to maximum correlation methods.
In this work, we show that great circles, the intersection of a plane through the origin and a sphere centered at the origin, can be perfectly recovered at their rate of innovation. Specifically, we show that 4K(8K − 7) + 7 samples are sufficient to perfectly recover K great circles, given an appropriate sampling scheme. Moreover, we argue that the number of samples can be reduced to 2K(4K − 1) while maintaining accurate results. This argument is supported by our numerical results. To improve the robustness to noise of our approach, we propose a modification that uses all the available information, instead of the critical amount. The increase in accuracy is demonstrated using numerical simulations.
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