Prof. Stephen P. Pereira Profile

Prof. Stephen P. Pereira

Professor of Hepatology & Gastroenterology at Univ College London

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Publications (18)

Proceedings Article | 7 August 2019 Presentation + Paper

Targeting of epidermal growth factor receptor (EGFR)-positive pancreatic cancer cell lines with cetuximab-conjugated near-infrared silver sulphide quantum dots

Peter Labib, Elnaz Yaghini, Mahshid Hashemkhani, Brian Davidson, Alexander MacRobert, Marilena Loizidou, Havva Acar, Stephen Pereira

Proceedings Volume 11070, 1107013 (2019) https://doi.org/10.1117/12.2525086

KEYWORDS: Toxicity, Receptors, Near infrared, Tumors, Surgery, Quantum dots, Luminescence, Silver, Pancreatic cancer

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Proceedings Article | 7 August 2019 Paper

Effect of 5-aminolevulinic acid on the haem biosynthesis pathway in pancreatic cancer and pancreatic ductal epithelial cell lines

Peter Labib, Walid Al-Akkad, Brian Davidson, Alexander MacRobert, Stephen Pereira

Proceedings Volume 11070, 110706K (2019) https://doi.org/10.1117/12.2525085

KEYWORDS: Pancreatic cancer, Luminescence, Cancer, Tissues, Surgery, Optical diagnostics, Tumors

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Proceedings Article | 7 August 2019 Presentation + Paper

5-aminolevulinic acid as a potential contrast agent for image-guided surgery in pancreatic cancer

Peter Labib, Elnaz Yaghini, Brian Davidson, Alexander MacRobert, Stephen Pereira

Proceedings Volume 11070, 110704R (2019) https://doi.org/10.1117/12.2525084

KEYWORDS: Cancer, Tissues, Image-guided intervention, Surgery, Pancreatic cancer, Luminescence, Fluorescent markers

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Proceedings Article | 7 August 2019 Presentation + Paper

Combination light-based therapies to treat pancreatic cancer: a proof of concept

A. Ney, I. Mahamed, A. Garcia-Sampedro, P. K. Selbo, P. Sancho, A. J. MacRobert, S. P. Pereira, P. Acedo

Proceedings Volume 11070, 1107045 (2019) https://doi.org/10.1117/12.2525305

KEYWORDS: Pancreatic cancer, Therapeutics, Photodynamic therapy, Toxicity, Cell death

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Proceedings Article | 19 April 2017 Presentation

Local pressure and matrix component effects on verteporfin distribution in pancreatic tumors (Conference Presentation)

Michael Nieskoski, Kayla Marra, Jason Gunn, Marvin Doyley, Kimberly Samkoe, Stephen Pereira, B. Stuart Trembly, Brian Pogue

Proceedings Volume 10047, 1004708 (2017) https://doi.org/10.1117/12.2249766

KEYWORDS: Targeting Task Performance metric, Tissues, Collagen, Therapeutics, Solids, Proteins, Tissue optics, Photodynamic therapy, Tumors, Tumor growth modeling

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Proceedings Article | 26 April 2016 Presentation

Photodynamic therapy with simultaneous suppression of multiple treatment escape pathways (Conference Presentation)

Bryan Spring, R. Bryan Sears, Lei Zheng, Zhiming Mai, Reika Watanabe, Margaret Sherwood, David Schoenfeld, Brian Pogue, Stephen Pereira, Elizabeth Villa, Tayyaba Hasan

Proceedings Volume 9694, 969409 (2016) https://doi.org/10.1117/12.2213828

KEYWORDS: Oncology, Cancer, Mouse models, Data modeling, Near infrared, Chromophores, Pancreatic cancer, Nanoparticles, Photodynamic therapy, Tumors

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Proceedings Article | 26 April 2016 Presentation

Critical dosimetry measures and surrogate tools that can facilitate clinical success in PDT (Conference Presentation)

Brian Pogue, Scott Davis, Stephen Kanick, Edward Maytin, Stephen Pereira, Akilan Palanisami, Tayyaba Hasan

Proceedings Volume 9694, 969405 (2016) https://doi.org/10.1117/12.2208777

KEYWORDS: Photodynamic therapy, Phase measurement, Solids, Tissues, Skin, Tumor growth modeling, Current controlled current source

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SPIE Journal Paper | 23 December 2013 Open Access

Contrast enhanced-magnetic resonance imaging as a surrogate to map verteporfin delivery in photodynamic therapy

Kimberley Samkoe, Amber Bryant, Jason Gunn, Stephen Pereira, Tayyaba Hasan, Brian Pogue

JBO, Vol. 18, Issue 12, 120504, (December 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.12.120504

KEYWORDS: Tumors, Magnetic resonance imaging, Photodynamic therapy, Tissues, Luminescence, Resonance enhancement, Gadolinium, Tissue optics, Pancreas, Computed tomography

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Proceedings Article | 13 March 2013 Paper

Pancreas tumor model in rabbit imaged by perfusion CT scans

Jason Gunn, Kenneth Tichauer, Karen Moodie, Susan Kane, Jack Hoopes, Errol Stewart, Jennifer Hadway, Ting-Yim Lee, Stephen Pereira, Brian Pogue

Proceedings Volume 8568, 85681E (2013) https://doi.org/10.1117/12.1518470

KEYWORDS: Abdomen, Scanners, Surgery, Blood circulation, Photodynamic therapy, Tumor growth modeling, Blood, Computed tomography, Pancreas, Tumors

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Proceedings Article | 13 March 2013 Paper

Photodynamic therapy of locally advanced pancreatic cancer (VERTPAC study): final clinical results

M. Huggett, M. Jermyn, A. Gillams, S. Mosse, E. Kent, S. Bown, T. Hasan, B. Pogue, S. Pereira

Proceedings Volume 8568, 85680J (2013) https://doi.org/10.1117/12.2013648

KEYWORDS: Head, Laser tissue interaction, Radiotherapy, Cancer, Liver, Pancreas, Fiber lasers, Pancreatic cancer, Computed tomography, Photodynamic therapy

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Proceedings Article | 13 March 2013 Paper

Photodynamic therapy light dose analysis of a patient based upon arterial and venous contrast CT scan information

Michael Jermyn, Scott Davis, Hamid Dehghani, Matthew Huggett, Tayyaba Hasan, Stephen Pereira, Brian Pogue

Proceedings Volume 8568, 85680Z (2013) https://doi.org/10.1117/12.2004003

KEYWORDS: Tissues, Computed tomography, Pancreas, Blood vessels, Photodynamic therapy, Image segmentation, Blood, Optical properties, Phototherapy, Tumors

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Proceedings Article | 11 February 2011 Paper

Photodynamic therapy of pancreatic cancer and elastic scattering spectroscopy of the duodenal mucosa for the detection of pancreaticobiliary malignancy

M. Huggett, R. N. Baddeley, N. Sandanayake, G. J. Webster, S. Bown, L. Lovat, A. Gillams, B. Pogue, T. Hasan, S. Pereira

Proceedings Volume 7886, 78860J (2011) https://doi.org/10.1117/12.874053

KEYWORDS: Tissues, Endoscopy, Safety, Diagnostics, Cancer, Scattering, Tissue optics, Spectroscopy, Pancreatic cancer, Photodynamic therapy

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Proceedings Article | 8 March 2010 Paper

Photodynamic therapy for locally advanced pancreatic cancer: early clinical results

N. Sandanayake, M. Huggett, S. Bown, B. Pogue, T. Hasan, S. Pereira

Proceedings Volume 7551, 75510L (2010) https://doi.org/10.1117/12.846555

KEYWORDS: Photodynamic therapy, Tumors, Pancreatic cancer, Pancreas, Tissues, Cancer, Liver, Computed tomography, Safety, Surgery

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Proceedings Article | 5 March 2010 Paper

In vivo sampling of Verteporfin uptake in pancreas cancer xenograft models: comparison of surface, oral, and interstitial measurements

Martin Isabelle, Julia O'Hara, Kimberley Samkoe, P. Jack Hoopes, Sandy Mosse, Stephen Pereira, Tayyaba Hasan, Brian Pogue

Proceedings Volume 7551, 755116 (2010) https://doi.org/10.1117/12.852779

KEYWORDS: Luminescence, In vivo imaging, Natural surfaces, Pancreas, Tumors, Photodynamic therapy, Laser induced fluorescence, Tissue optics, Tissues, Picosecond phenomena

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Proceedings Article | 13 July 2009 Paper

Effect of verteporfin-PDT on the Notch signaling pathway in cholangiocarcinoma (CCA) cell lines

Virginie Cerec, Fausto Andreola, Stephen Pereira

Proceedings Volume 7380, 73806J (2009) https://doi.org/10.1117/12.828411

KEYWORDS: Oncology, Therapeutic agents, Solids, Proteins, In vitro testing, Tumors, Cancer, Receptors, Photodynamic therapy, Simulation of CCA and DLA aggregates

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Proceedings Article | 13 July 2009 Paper

Effect of verteporfin-PDT on epithelial growth factor receptor (EGFR) signaling pathway in cholangiocarcinoma cell lines

Fausto Andreola, Virginie Cerec, Stephen Pereira

Proceedings Volume 7380, 73806P (2009) https://doi.org/10.1117/12.828272

KEYWORDS: Confocal microscopy, Resistance, In vitro testing, Modulation, Cancer, Simulation of CCA and DLA aggregates, Proteins, Cell death, Receptors, Photodynamic therapy

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