Mr. Ting Chean Khoo Profile

Ting Chean Khoo

at Massachusetts general hospital

SPIE Involvement:

Author

Publications (14)

Proceedings Article | 13 March 2024 Presentation

Dual modality monitoring of topical formulations within human skin using stimulated Raman scattering (SRS) microscope

Dandan Tu, Nick-Sidney Lemberger, Kristin Wallmeier, Jackson Riseman, Benjamin Kuzma, Yuxiao Wei, Ting Chean Khoo, Priyanka Ghosh, Sam Raney, Markham Luke, Carsten Fallnich, Conor Evans

Proceedings Volume PC12821, PC1282104 (2024) https://doi.org/10.1117/12.3001122

KEYWORDS: Skin, Raman scattering, Near infrared, Microscopes, Signal intensity, Light scattering, Tissue optics, Temporal resolution, Signal attenuation, Photons

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Proceedings Article | 12 March 2024 Presentation + Paper

Measuring methamphetamine induced morphology changes in apoptotic glial cells using the transport of intensity equation, digital holographic microscopy, and diffraction tomography

Shane Carney, Alireza Sheikhsofla, Ting Chean Khoo, Samaneh Ghazanfarpour, Monireh Pourrahimi, Arthur Redgate, Stephen Rose, Madison Torres, Anna Sharikova, Supriya Mahajan, Jonathan Petruccelli, Alexander Khmaladze

Proceedings Volume 12854, 128540I (2024) https://doi.org/10.1117/12.3003357

KEYWORDS: Cell death, Digital holography, Optical path differences, Holography, Phase imaging, Microscopy, Diffraction

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Proceedings Article | 16 March 2023 Presentation + Paper

Assessment of Raman hyperspectral spectra upon depletion of proteins involved in iron transport

Pampa Mandal, Alireza Sheikhsofla, Samaneh Ghazanfarpour, Ting Chean Khoo, Jonathan Barra, Isaiah Crousborne, Anna Sharikova, Alexander Khmaladze, Margarida Barroso

Proceedings Volume 12391, 123910L (2023) https://doi.org/10.1117/12.2650402

KEYWORDS: Raman spectroscopy, Iron, Singular value decomposition, Proteins, Breast cancer, Chemical analysis, Ablation, Visualization

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Proceedings Article | 27 May 2022 Paper

The study of cell death mechanisms via simultaneous Raman and transport of intensity phase-imaging techniques

Shane Carney, Ting Chean Khoo, Jonathan Barra-Carrasco, Samaneh Ghazanfarpour, Shahab Bahreini, Anna Sharikova, Margarida Barroso, Supriya Mahajan, Jonathan Petruccelli, Alexander Khmaladze

Proceedings Volume 12144, 121440A (2022) https://doi.org/10.1117/12.2622411

KEYWORDS: Raman spectroscopy, Cell death, Breast cancer, Microscopes, Integrated optics, Digital holography, Tissues, Temporal coherence, Spectroscopy, Phase measurement

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Proceedings Article | 2 March 2022 Presentation + Paper

Quantitative volume comparisons of methamphetamine-induced apoptosis by simultaneous digital holographic microscopy and transport of intensity phase-imaging techniques

Shane Carney, Ting Chean Khoo, Kate Tubbesing, Anna Sharikova, Supriya Mahajan, Jonathan Petruccelli, Alexander Khmaladze

Proceedings Volume 11972, 119720B (2022) https://doi.org/10.1117/12.2610394

KEYWORDS: Cell death, Digital holography, Microscopy, Microscopes, Holography, Beam splitters, Cameras, Objectives, Mirrors

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Proceedings Article | 5 March 2021 Presentation + Paper

Raman mapping of transferrin and ferritin distributions in breast cancer cells

Kate Tubbesing, Ting Chean Khoo, Anna Sharikova, Margarida Barroso, Alexander Khmaladze

Proceedings Volume 11655, 1165518 (2021) https://doi.org/10.1117/12.2579413

KEYWORDS: Breast cancer, Iron, Raman spectroscopy, Fourier transforms, Proteins, Statistical analysis, Receptors, Hyperspectral imaging, Cancer

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Proceedings Article | 2 April 2020 Presentation + Paper

Measurements of iron-bound transferrin in breast cancer tumor xenografts using Raman spectral imaging

Kate Tubbesing, Ting Chean Khoo, Alena Rudkouskaya, Anna Sharikova, Margarida Barroso, Alexander Khmaladze

Proceedings Volume 11363, 113630Y (2020) https://doi.org/10.1117/12.2555211

KEYWORDS: Tumors, Raman spectroscopy, Iron, Breast cancer, Tissues, Imaging spectroscopy, Cancer, Confocal microscopy, Veins, Receptors

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Proceedings Article | 20 February 2020 Presentation + Paper

Digital holographic microscopy (DHM) and transport of intensity (TIE) phase imaging of live cells

Shane Carney, Ting Chean Khoo, Jeremy Wittkopp, Kai Pisila, Georgios Athanassiadis, Anna Sharikova, Alexander Khmaladze, Jonathan Petruccelli

Proceedings Volume 11251, 1125122 (2020) https://doi.org/10.1117/12.2547934

KEYWORDS: Digital holography, Phase imaging, Holography, Microscopy, Diffraction, Microscopes

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Proceedings Article | 20 February 2020 Presentation + Paper

Raman hyperspectral imaging of transferrin-bound iron in T47D and MDA-MB-231 breast cancer cells

Ting Chean Khoo, Kate Tubbesing, Alena Rudkouskaya, Georgios Athanassiadis, Anna Sharikova, Margarida Barroso, Alexander Khmaladze

Proceedings Volume 11251, 112511E (2020) https://doi.org/10.1117/12.2547638

KEYWORDS: Iron, Raman spectroscopy, Breast cancer, Hyperspectral imaging, Cancer, Imaging spectroscopy, Receptors, Proteins, Tissues, Microscopy

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Proceedings Article | 20 February 2020 Presentation + Paper

Detection of the differentiation state of salivary gland organoids for tissue engineering by Raman spectroscopy

Ting Chean Khoo, Nicholas Moskwa, Georgios Athanassiadis, Anna Sharikova, Melinda Larsen, Alexander Khmaladze

Proceedings Volume 11251, 1125103 (2020) https://doi.org/10.1117/12.2547636

KEYWORDS: Raman spectroscopy, Tissues, In vivo imaging, Tissue engineering, Regenerative medicine, Proteins, Spectroscopy, Imaging spectroscopy, Systems modeling, Microscopes

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SPIE Journal Paper | 25 April 2019 Open Access

Methamphetamine-induced apoptosis in glial cells examined under marker-free imaging modalities

Lianna Y. D’Brant, Habben Desta, Ting Chean Khoo, Anna V. Sharikova, Supriya D. Mahajan, Alexander Khmaladze

JBO, Vol. 24, Issue 04, 046503, (April 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.4.046503

KEYWORDS: Cell death, Raman spectroscopy, Glia, 3D image processing, Digital holography, Proteins, Control systems, Microscopes, Microscopy, Tomography

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Proceedings Article | 4 March 2019 Paper

Raman hyperspectral imaging of transferrin-bound iron in cancer cells

Ting Chean Khoo, Kate Tubbesing, Cat Pham, Habben Desta, Anna Sharikova, Margarida Barroso, Alexander Khmaladze

Proceedings Volume 10890, 108901R (2019) https://doi.org/10.1117/12.2511397

KEYWORDS: Iron, Raman spectroscopy, Breast cancer, Cancer, Hyperspectral imaging, Proteins, Imaging spectroscopy, Tissues, Spectroscopy

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Proceedings Article | 4 March 2019 Paper

Raman hyperspectral imaging of different salivary gland cell types for tissue engineering

Ting Chean Khoo, Nicholas Moskwa, Anna Sharikova, Melinda Larsen, Alexander Khmaladze

Proceedings Volume 10890, 108901S (2019) https://doi.org/10.1117/12.2511396

KEYWORDS: Raman spectroscopy, Tissues, In vivo imaging, Tissue engineering, Proteins, Regenerative medicine, Hyperspectral imaging, Stem cells, Microscopes, In vitro testing

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Proceedings Article | 5 June 2018 Paper

Design of a dual wavelength digital holographic imaging system for the examination of layered structures

John McFarland, Ting Chean Khoo, Anna Sharikova, Alexander Khmaladze

Proceedings Volume 10690, 1069013 (2018) https://doi.org/10.1117/12.2312274

KEYWORDS: Holography, Digital holography, Reflectivity, Reconstruction algorithms, 3D image reconstruction, Imaging systems, Optical design, Phase imaging, Electrodes, Microscopy

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Showing 5 of 14 publications

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