Prof. Brendan F. Kennedy Profile

Prof. Brendan F. Kennedy

Professor at Harry Perkins Institute of Medical Research

SPIE Involvement:

Conference Program Committee | Author

Publications (56)

Proceedings Article | 20 June 2024 Presentation

Micro-scale assessment of breast cancer elasticity using optical coherence elastography

Rowan Sanderson, Ken Foo, Renate Zilkens, Imogen Boman, Lee Jackson, Jose Cid Fernandez, Benjamin Dessauvagie, Chris Yeomans, Anmol Rijhumal, Saud Hamza, Christobel Saunders, Brendan Kennedy

Proceedings Volume PC13006, PC130060J (2024) https://doi.org/10.1117/12.3016862

KEYWORDS: Breast cancer, Tissues, Optical coherence, Elastography, Elasticity, Cancer, Breast, Surgery, Reproducibility, Radiotherapy

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Proceedings Article | 19 June 2024 Presentation

Novel mechanical contrast in optical coherence elastography based on tissue heterogeneity

Brendan Kennedy, Jiayue Li, Ken Foo, Rowan Sanderson, Renate Zilkens, Anmol Rijhumal, Mireille Hardie, Christobel Saunders

Proceedings Volume PC13010, PC130100G (2024) https://doi.org/10.1117/12.3029505

KEYWORDS: Tissues, Optical coherence, Elastography, Nervous system, Deformation, Breast, Voxels, Optical coherence tomography, Elasticity, 3D image processing

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Proceedings Article | 13 March 2024 Presentation

Optical coherence mechano-microscopy for biomechanical characterization of 3D cancer models

Alireza Mowla, Matt Hepburn, Jiayue Li, Danielle Vahala, Sebastian Amos, Liisa Hirvonen, Rowan Sanderson, Philip Wijesinghe, Samuel Maher, Yu Suk Choi, Brendan Kennedy

Proceedings Volume PC12844, PC1284406 (2024) https://doi.org/10.1117/12.3005758

KEYWORDS: 3D modeling, Cancer, Optical coherence, Tumor growth modeling, Biomechanics, 3D metrology, Fluorescence, Elasticity, Confocal microscopy, Compliance

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Proceedings Article | 13 March 2024 Presentation

Three-dimensional characterization of murine ovary elasticity using quantitative micro-elastography.

Matt Hepburn, Anna Jaeschke, Alireza Mowla, Chii Chan, Brendan Kennedy

Proceedings Volume PC12844, PC128440B (2024) https://doi.org/10.1117/12.3006718

KEYWORDS: Elasticity, Ovary, Tissues, Atomic force microscopy, Optical coherence, Fallopian tube, Elastography, Diseases and disorders, Biology

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Proceedings Article | 13 March 2024 Presentation

Investigation of optical coherence tomography and elastography for visualization of human prostate microarchitecture

Marta Skrok, Tamborski Szymon, Matt Hepburn, Qi Fang, Mateusz Maniewski, Marek Zdrenka, Maciej Szkulmowski, Adam Kowalewski, Brendan Kennedy, Łukasz Szylberg

Proceedings Volume PC12831, PC128310H (2024) https://doi.org/10.1117/12.3023391

KEYWORDS: Optical coherence tomography, Prostate, Elastography, Visualization, Surgery, Prostate cancer, Cancer, Tissues, Tissue optics, Standards development

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Proceedings Article | 13 March 2024 Presentation

Three-dimensional displacement retrieval in optical coherence elastography

Balázs Dura-Kovács, Andrea Mazzolani, Jakub Zálešák, Jiayue Li, Matt Hepburn, Brendan Kennedy, Peter R. Munro

Proceedings Volume PC12830, PC1283028 (2024) https://doi.org/10.1117/12.3005628

KEYWORDS: Optical coherence, Elastography, Tissues, Optical coherence tomography, Speckle pattern, Speckle

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Proceedings Article | 13 March 2024 Presentation

Dynamic optical coherence microscopy integrated with confocal fluorescence microscopy to study cell migration in 3D cancer models

Alireza Mowla, Philip Wijesinghe, Jiayue Li, Matt Hepburn, Sebastian Amos, Danielle Vahala, Liisa Hirvonen, Samuel Maher, Yu Suk Choi, Brendan Kennedy

Proceedings Volume PC12830, PC128302J (2024) https://doi.org/10.1117/12.3005748

KEYWORDS: 3D modeling, Confocal microscopy, Cancer, Optical coherence microscopy, Fluorescence microscopy, Tumor growth modeling, Data acquisition, Spectroscopy, Photonics, Objectives

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Proceedings Article | 11 August 2023 Paper

Multimodal optical coherence microscopy, mechano-microscopy, and fluorescence microscopy for three-dimensional characterization of multicellular spheroids

Alireza Mowla, Matt Hepburn, Jiayue Li, Liisa Hirvonen, Danielle Vahala, Sebastian Amos, Samuel Maher, Yu Suk Choi, Brendan Kennedy

Proceedings Volume 12632, 1263219 (2023) https://doi.org/10.1117/12.2670830

KEYWORDS: Optical coherence microscopy, Fluorescence microscopy, 3D scanning, Fluorescence, Tunable filters, Optical filters, Imaging systems, Elasticity, Compliance, Beam splitters

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Proceedings Article | 11 August 2023 Paper

Friction in quantitative micro-elastography

Kai Metzner, Qi Fang, Rowan Sanderson, Alireza Mowla, Brendan Kennedy

Proceedings Volume 12632, 1263214 (2023) https://doi.org/10.1117/12.2669463

KEYWORDS: Elasticity, Biological samples, Viscosity, Tissues, Biological imaging, Optical coherence tomography, Elastography

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Proceedings Article | 17 March 2023 Presentation

Dynamic full-field optical coherence microscopy of early mammalian oocytes

Seweryn Morawiec, Patrycjusz Stremplewski, Anna Ajduk, Brendan Kennedy, Maciej Szkulmowski

Proceedings Volume PC12363, PC123630P (2023) https://doi.org/10.1117/12.2649882

KEYWORDS: Optical coherence microscopy, Luminescence, Temporal resolution, Temporal coherence, Speckle, Spatial resolution, Phase shifts, Phase shift keying, Modulation, Mirrors

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Proceedings Article | 15 March 2023 Presentation

Quantitative micro-elastography for biomechanical evaluation of chronic liver injury in mouse models (Conference Presentation)

Alireza Mowla, Brendan Kennedy, George Yeoh, Rose Belford, Nina Tirnitz-Parker, Julia Koehn, Nathan Main

Proceedings Volume PC12381, PC123810B (2023) https://doi.org/10.1117/12.2647333

KEYWORDS: Liver, Mouse models, Injuries, Elastography, Tissues, Optical coherence tomography, Liver cancer, Collagen

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Proceedings Article | 15 March 2023 Presentation

Improving strain retrieval in compression optical coherence elastography in the presence of speckle (Conference Presentation)

Peter R. Munro, Balázs Dura-Kovács, Andrea Mazzolani, Jakub Zalesak, Jiayue Li, Matt Hepburn, Brendan Kennedy

Proceedings Volume PC12381, PC1238104 (2023) https://doi.org/10.1117/12.2649894

KEYWORDS: Image compression, Tissue optics, Elastography, Coherence (optics), Tissues, Speckle pattern, Optical coherence tomography, Speckle, Signal to noise ratio

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Proceedings Article | 15 March 2023 Presentation

Development of wireless cost-effective optical elastography probe towards intraoperative breast cancer detection (Conference Presentation)

Qi Fang, Aiden Taba, Seokhyun Choi, Kyle Newman, Renate Zilkens, Imogen Boman, Rowan Sanderson, Brendan Kennedy

Proceedings Volume PC12381, PC123810P (2023) https://doi.org/10.1117/12.2650857

KEYWORDS: Elastography, Breast cancer, Tissues, Cancer, Breast, Surgery, Real time imaging, Optical coherence tomography, Cameras, Tissue optics

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Proceedings Article | 15 March 2023 Presentation

Mapping the micro-scale strain tensor using tension-based optical coherence elastography (Conference Presentation)

Jiayue Li, Alireza Mowla, Ziming Chen, Matt Hepburn, Lixin Chin, Minghao Zheng, Brendan Kennedy

Proceedings Volume PC12381, PC123810A (2023) https://doi.org/10.1117/12.2647214

KEYWORDS: Tissues, Tissue optics, Elastography, Coherence (optics), Biomedical optics, 3D image processing, Optical coherence tomography, Mechanics, Finite element methods

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Proceedings Article | 9 March 2023 Presentation

Subcellular mechano-microscopy for mechanobiology of 3D cell spheroid cultures

Alireza Mowla, Brendan Kennedy, Matt Hepburn, Jiayue Li, Yu Suk Choi, Samuel Maher, Danielle Vahala

Proceedings Volume PC12367, PC123671C (2023) https://doi.org/10.1117/12.2647323

KEYWORDS: Microscopy, Luminescence, Statistical analysis, Silicon, Optical coherence tomography, Optical coherence microscopy, Objectives, Elastography, Breast cancer, Actuators

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Proceedings Article | 9 March 2023 Presentation

Highly sensitive and robust strain retrieval in optical coherence elastography

Balazs Dura-Kovacs, Andrea Mazzolani, Jakub Zalesak, Jiayue Li, Matt Hepburn, Brendan Kennedy, Peter R. Munro

Proceedings Volume PC12367, PC1236717 (2023) https://doi.org/10.1117/12.2649798

KEYWORDS: Tissue optics, Elastography, Coherence (optics), Tissues, Speckle pattern, Optical coherence tomography, Speckle, Signal to noise ratio

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Proceedings Article | 9 March 2023 Presentation

In vivo quantitative micro-elastography for detection of residual cancer during breast-conserving surgery

Peijun Gong, Synn Lynn Chin, Wes Allen, Helen Ballal, James Anstie, Lixin Chin, Hina Ismail, Renate Zilkens, Devina Lakhiani, Matthew McCarthy, Qi Fang, Daniel Firth, Kyle Newman, Caleb Thomas, Jiayue Li, Rowan Sanderson, Ken Foo, Chris Yeomans, Benjamin Dessauvagie, Bruce Latham, Christobel Saunders, Brendan Kennedy

Proceedings Volume PC12367, PC1236715 (2023) https://doi.org/10.1117/12.2652919

KEYWORDS: In vivo imaging, Cancer, Surgery, Breast cancer, Elastography, Coherence (optics)

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Proceedings Article | 6 March 2023 Presentation

Low-resource and cost-effective camera-based optical palpation for breast cancer detection and burn scar assessment

Qi Fang, Rowan Sanderson, Seokhyun Choi, Aiden Taba, Andrea Curatolo, Devina Lakhiani, Renate Zilkens, Kyle Newman, Benjamin Dessauvagie, Helen DeJong, Fiona Wood, Christobel Saunders, Brendan Kennedy

Proceedings Volume PC12369, PC1236904 (2023) https://doi.org/10.1117/12.2650883

KEYWORDS: Tissue optics, Cameras, Breast cancer, Elastography, Silicon, Optical imaging, Imaging systems, Biomedical optics, Tissues, Telemedicine

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Proceedings Article | 6 March 2023 Presentation

In-cavity detection of residual cancer during breast-conserving surgery using in vivo quantitative micro-elastography

Proceedings Volume PC12368, PC1236804 (2023) https://doi.org/10.1117/12.2651033

KEYWORDS: Cancer, Surgery, In vivo imaging, Breast cancer, Tissues, Diagnostics, Breast, Visualization

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Proceedings Article | 9 December 2021 Paper

Characterizing the elasticity of skeletal muscle using quantitative micro-elastography

Jiayue Li, Erin Lloyd, Matt Hepburn, Alireza Mowla, Yu Suk Choi, Miranda Grounds, Brendan Kennedy

Proceedings Volume 11924, 119240Q (2021) https://doi.org/10.1117/12.2616056

KEYWORDS: Tissues, Optical coherence tomography, Natural surfaces, Glasses, Scattering, Medical research, Interfaces, Ultraviolet radiation, Tissue optics, Statistical analysis

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Proceedings Article | 9 March 2020 Presentation

Characterizing the elasticity of thin silk biomaterials using quantitative micro-elastography (Conference Presentation)

Matt Hepburn, Filippo Valente, Phillip Wijesinghe, Rodney Dilley, Brendan Kennedy

Proceedings Volume 11242, 1124206 (2020) https://doi.org/10.1117/12.2548513

KEYWORDS: 3D printing, Image compression, Tissue optics, Elastography, Image quality, Lithography, Coherence (optics), 3D image processing, Natural surfaces, Silicon

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Proceedings Article | 9 March 2020 Presentation

Comparison between two handheld quantitative micro elastography methods (Conference Presentation)

Qi Fang, Luke Frewer, Renate Zilkens, Lixin Chin, Ken Foo, Rowan Sanderson, Devina Lakhiani, James Anstie, Ben Dessauvagie, Bruce Latham, Christobel Saunders, Brendan Kennedy

Proceedings Volume 11242, 1124210 (2020) https://doi.org/10.1117/12.2549443

KEYWORDS: Ferroelectric materials, Elastography, Tissues, Breast, Actuators, Mammography, Surgery, Optical coherence tomography, Silicon, Tumors

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Proceedings Article | 13 March 2019 Presentation

An assessment of OCT plus micro-elastography for detection of close tumor margins following breast-conserving surgery (Conference Presentation)

Kelsey Kennedy, Wes Allen, Renate Zilkens, Ken Foo, Qi Fang, Lixin Chin, Rowan Sanderson, James Anstie, Synn Lynn Chin, Benjamin Dessauvagie, Bruce Latham, Christobel Saunders, Brendan Kennedy

Proceedings Volume 10856, 108560G (2019) https://doi.org/10.1117/12.2510588

KEYWORDS: Surgery, Optical coherence tomography, Tumors, Tissues, Cancer, Elastography, Breast, Breast cancer, Oncology, Tissue optics

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